444321-95-3

Upstream product

• 88-05-1 2,4,6-trimethylaniline 
• 444325-38-6 N-2,4,6-trimethylphenyl-(1,2-diaminoethane) 
• 444325-39-7 1-(2,4,6-trimethyl-phenyl)-imidazolidin-2-ylideneamine 
• 444325-41-1 2-methyl-7-(2,4,6-trimethyl-phenyl)-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid ethyl ester 
• 26389-60-6 N-(n-propyl)-N-(cyclopropanemethyl)amine 

Relevant academic research and scientific papers

Synthesis, structure-activity relationships, and anxiolytic activity of 7-aryl-6,7-dihydroimidazoimidazole corticotropin-releasing factor 1 receptor antagonists

7-Aryl-6,7-dihydroimidazoimidazoles represent a novel series of high-affinity corticotropin-releasing factor 1 receptor antagonists. Here, we report their synthesis and SAR as well as behavioral activity of two exemplary compounds, 7b and 7k, in a mouse canopy model of anxiety.