444335-12-0

Basic information

• Product Name: 7-[4-[4-[5(S)-(Acetamidomethyl)-2-oxooxazolidin-3-yl]-2-fluorophenyl]piperazin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• Synonyms: MCB-116
• CAS NO: 444335-12-0
• Molecular Formula: C₂₉H₂₉F₂N₅O₆
• Molecular Weight: 581.58118
• Mol File: 444335-12-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-[4-[4-[5(S)-(Acetamidomethyl)-2-oxooxazolidin-3-yl]-2-fluorophenyl]piperazin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[4-[4-[5(S)-(Acetamidomethyl)-2-oxooxazolidin-3-yl]-2-fluorophenyl]piperazin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(444335-12-0)
• EPA Substance Registry System: 7-[4-[4-[5(S)-(Acetamidomethyl)-2-oxooxazolidin-3-yl]-2-fluorophenyl]piperazin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(444335-12-0)

Safety Data

• Hazardous Substances Data: 444335-12-0(Hazardous Substances Data)

Upstream product

• 154590-66-6 (S)-N-[[3-[3-fluoro-4-(1-piperazinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide 
• 119489-54-2 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid boron diacetate 
• 86393-33-1 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid 

Relevant articles and documents

Design, synthesis and biological evaluation of oxazolidinone-quinolone hybrids

Oxazolidinone-quinolone hybrids that combine the pharmacophores of a quinolone and an oxazolidinone were synthesised and shown to be active against a variety of resistant and susceptible Gram-positive and fastidious Gram-negative organisms. The best compo