4445-36-7Relevant academic research and scientific papers
Synthesis of dibenzo[d,f]-1,2-selena and -1,2-thiazepin-3-ones derivatives, bis-homoebselen
Mohsine, Abdelaziz,Christiaens, Leon
, p. 2567 - 2593 (2007/10/03)
Dibenzo[d,f]-1,2-selena and -1,2-thiazepin-3-ones derivatives were prepared from the corresponding 2-alkylselanyl- and 2-alkylsulfanylbiphenyl-2′-carboxamides or their diselenide or disulfide derivatives. These new seven-membered seleno-compounds are homologues of Ebselen (PZ51) (1) which exhibits glutathion peroxidase activity. Bis-homologues of PZ25 (2) were also synthesized. Synthesis of benzo[c]selenocoumarin.
