444573-52-8Relevant academic research and scientific papers
Molecular design of anti-MRSA agents based on the anacardic acid scaffold
Green, Ivan R.,Tocoli, Felismino E.,Lee, Sang Hwa,Nihei, Ken-ichi,Kubo, Isao
, p. 6236 - 6241 (2007)
A series of anacardic acid analogues possessing different side chains viz. phenolic, branched, and alicyclic were synthesized and their antibacterial activity tested against methicillin-resistant Staphylococcus aureus (MRSA). The maximum activity against
Synthesis of an unnatural anacardic acid analogue
Green, Ivan R.,Tocoli, Felismino E.
, p. 947 - 957 (2007/10/03)
The unnatural E isomer of anacardic acid 7 has been synthesized employing the following key steps: Swern oxidation of a diastereoisomeric mixture of β-hydroxyphosphine oxides 13a/b to the corresponding ketone 14 followed by stereo-specific reduction to th
