444574-79-2Relevant academic research and scientific papers
New potent calcimimetics: I. Discovery of a series of novel trisubstituted ureas
Temal, Taoues,Jary, Hélène,Auberval, Marielle,Lively, Sarah,Guédin, Denis,Vevert, Jean-Paul,Deprez, Pierre
, p. 2451 - 2454 (2013/05/09)
Starting from Fendiline and R-568, we identified a novel series of urea compounds as positive allosteric modulators of the calcium sensing receptor (CaSR), as part of a program to identify novel therapeutics for secondary hyperparathyroidism. Initially id
DERIVATlVES OF UREA AND RELATED DIAMINES, METHODS FOR THEIR MANUFACTURE AND USES THEREFOR
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Page/Page column 72-73, (2009/03/07)
The present invention relates generally to compounds represented in Formula I, pharmaceutical compositions comprising them and methods of treating of diseases or disorders related to the function of the calcium sensing receptor. The invention also relates to processes for making such compounds and to intermediates useful in these processes
