444588-17-4 Usage
Uses
Used in Pharmaceutical Industry:
7-Nitro-2,3,4,5-tetrahydro-1H-benzo[b]azepine is used as a chemical intermediate for the synthesis of various medicinally important compounds. Its nitro group allows for further chemical modifications, making it a versatile building block in the development of new pharmaceuticals.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 7-Nitro-2,3,4,5-tetrahydro-1H-benzo[b]azepine is utilized as a subject of study for understanding structure-activity relationships. Its unique structure and properties contribute to the advancement of drug design and discovery processes, aiding in the identification of potential therapeutic agents.
Used in Drug Design and Discovery:
7-Nitro-2,3,4,5-tetrahydro-1H-benzo[b]azepine is employed as a structural template in drug design and discovery. Its bicyclic benzo[b]azepine ring system provides a foundation for the development of novel compounds with potential therapeutic applications, particularly in the area of antidepressant medications.
Check Digit Verification of cas no
The CAS Registry Mumber 444588-17-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,4,5,8 and 8 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 444588-17:
(8*4)+(7*4)+(6*4)+(5*5)+(4*8)+(3*8)+(2*1)+(1*7)=174
174 % 10 = 4
So 444588-17-4 is a valid CAS Registry Number.
444588-17-4Relevant academic research and scientific papers
OXAZOLIDINONE DERIVATES N-SUBSTITUTED BY A TRICYCLIC RING, FOR USE AS ANTIBACTERIAL AGENTS
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Page/Page column 105, (2010/02/08)
Compounds of formula (I) and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula (I) as well as pharmaceutically acceptable compositions comprising compounds of formula (I). Compounds of formula (I) as disclosed herein can be used in a variety of applications including use as antibacterial P is a tricyclic ring system as defined in claiml.
Synthesis and biological evaluation of benzazepine oxazolidinone antibacterials
Johnson, Paul D.,Aristoff, Paul A.,Zurenko, Gary E.,Schaadt, Ronda D.,Yagi, Betty H.,Ford, Charles W.,Hamel, Judith C.,Stapert, Douglas,Moerman, Judy K.
, p. 4197 - 4200 (2007/10/03)
Novel benzazepine oxazolidinone antibacterials were synthesized and evaluated against clinically relevant susceptible and resistant organisms. The effect of ring nitrogen position and N-substitution on antibacterial activity is examined.
Oxazolidinones having a benzannulated 6- or 7-membered heterocycle
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, (2008/06/13)
The present invention provides oxazolidinones having a benzannelated 6- or 7-membered heterocycle as antibacterial agents.
