444588-18-5Relevant academic research and scientific papers
OXAZOLIDINONE DERIVATIVES N-SUBSTITUTED BY A BICYCLIC RING, FOR USE AS ANTIBACTERIAL AGENTS
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Page/Page column 105, (2010/02/08)
Compounds of formula (I) and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula (I) as well as pharmaceutically acceptable compositions comprising compounds of formula (I). Compoun
OXAZOLIDINONE DERIVATES N-SUBSTITUTED BY A TRICYCLIC RING, FOR USE AS ANTIBACTERIAL AGENTS
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Page/Page column 106, (2010/02/08)
Compounds of formula (I) and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula (I) as well as pharmaceutically acceptable compositions comprising compounds of formula (I). Compounds of formula (I) as disclosed herein can be used in a variety of applications including use as antibacterial P is a tricyclic ring system as defined in claiml.
Synthesis and biological evaluation of benzazepine oxazolidinone antibacterials
Johnson, Paul D.,Aristoff, Paul A.,Zurenko, Gary E.,Schaadt, Ronda D.,Yagi, Betty H.,Ford, Charles W.,Hamel, Judith C.,Stapert, Douglas,Moerman, Judy K.
, p. 4197 - 4200 (2007/10/03)
Novel benzazepine oxazolidinone antibacterials were synthesized and evaluated against clinically relevant susceptible and resistant organisms. The effect of ring nitrogen position and N-substitution on antibacterial activity is examined.
