444643-86-1

Basic information

• Product Name: Propanoic acid, 2,2-dimethyl-, 3,4-dihydro-4-hydroxy-4-[(4-hydroxyphenyl)methyl]-3-(4-methoxyphenyl)- 2H-1-benzopyran-7-yl ester
• CAS NO: 444643-86-1
• Molecular Formula: C28H30O6
• Molecular Weight: 462.543
• Mol File: 444643-86-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2,2-dimethyl-, 3,4-dihydro-4-hydroxy-4-[(4-hydroxyphenyl)methyl]-3-(4-methoxyphenyl)- 2H-1-benzopyran-7-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2,2-dimethyl-, 3,4-dihydro-4-hydroxy-4-[(4-hydroxyphenyl)methyl]-3-(4-methoxyphenyl)- 2H-1-benzopyran-7-yl ester(444643-86-1)
• EPA Substance Registry System: Propanoic acid, 2,2-dimethyl-, 3,4-dihydro-4-hydroxy-4-[(4-hydroxyphenyl)methyl]-3-(4-methoxyphenyl)- 2H-1-benzopyran-7-yl ester(444643-86-1)

Safety Data

• Hazardous Substances Data: 444643-86-1(Hazardous Substances Data)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 485-72-3 7-Hydroxy-3-(4-methoxy-phenyl)-chromen-4-on 
• 444643-84-9 2,2-dimethyl-propanoic acid 3,4-dihydro-3-(4-methoxyphenyl)-4-oxo-2H-1-benzopyran-7-yl ester 
• 444643-83-8 2,2-dimethyl-propanoic acid 3-(4-methoxyphenyl)-4-oxo-4H-1-benzopyran-7-yl ester 

Downstream Products

• 738601-59-7 3,4-dihydro-3-(4-methoxyphenyl)-4-[[4-[3-(1-piperidinyl)propoxy]phenyl]methyl]-2H-1-benzopyran-4,7-diol 
• 738601-60-0 -4-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-3,4-dihydro-3-(4-methoxyphenyl)-2H-1-benzopyran-4,7-diol 
• 444643-88-3 3,4-dihydro-3-(4-methoxyphenyl)-4-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]-2H-1-benzopyran-4,7-diol 
• 738601-57-5 3,4-dihydro-3-(4-methoxyphenyl)-4-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]methyl]-2H-1-benzopyran-4,7-diol 
• 444643-87-2 2,2-dimethyl-propanoic acid 3,4-dihydro-4-hydroxy-3-(4-methoxyphenyl)-4-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]-2H-1-benzopyran-7-yl ester 
• 738601-50-8 2,2-dimethyl-propanoic acid 4-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-3,4-dihydro-4-hydroxy-3-(4-methoxyphenyl)-2H-1-benzopyran-7-yl ester 
• 738601-49-5 2,2-dimethyl-propanoic acid 3,4-dihydro-4-hydroxy-3-(4-methoxyphenyl)-4-[[4-[3-(1-piperidinyl)propoxy]phenyl]methyl]-2H-1-benzopyran-7-yl ester 
• 738601-47-3 2,2-dimethyl-propanoic acid 3,4-dihydro-4-hydroxy-3-(4-methoxyphenyl)-4-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]methyl]-2H-1-benzopyran-7-yl ester 

Relevant articles and documents

Synthesis, pharmacological evaluation, and structure-activity relationships of benzopyran derivatives with potent SERM activity

The synthesis, binding affinity for estrogen receptor subtypes (ERα and ERβ) and pharmacological activity on rat uterus of a new class of potent ligands, characterized by a 3-phenylbenzopyran scaffold with a basic side chain in position 4, are reported. S