444717-82-2Relevant academic research and scientific papers
Studies on azole-to-azole interconversion - An interesting case of absence of a "primary steric effect" in the ring-degenerate equilibration between ortho-substituted 3-aroylamino-5-methyl-1,2,4-oxadiazoles and 3-acetylamino-5-aryl-1,2,4-oxadiazoles in me
Buscemi, Silvestre,Frenna, Vincenzo,Pace, Andrea,Vivona, Nicolo,Cosimelli, Barbara,Spinelli, Domenico
, p. 1417 - 1423 (2007/10/03)
The title reaction has been studied by 1H NMR, both in CD3OD and in tBuOK/CD3OD. The components of the electronic effect of the substituent on the benzene ring show different contributions depending on whether the equilibr
A generalized synthesis of 3-amino-5-aryl-, 3-amino-5-polyfluorophenyl-, and 3-amino-5-alkyl-1,2,4-oxadiazoles through ring-degenerate rearrangements
Buscemi, Silvestre,Pace, Andrea,Frenna, Vincenzo,Vivona, Nicolo?
, p. 811 - 823 (2007/10/03)
A generalized synthesis of 3-amino-5-aryl-, 3-amino-5-polyfluorophenyl- and 3-amino-5-alkyl-1,2,4-oxadiazoles has been developed starting from the 3-amino-5-methyl-1,2,4-oxadiazole as a common synthon. Aroylation or alkanoylation of this aminooxadiazole,
