444760-02-5Relevant academic research and scientific papers
Synthetic studies toward SNF4435 C and SNF4435 D.
Beaudry, Christopher M,Trauner, Dirk
, p. 2221 - 2224 (2002)
[reaction: see text] A synthetic approach toward the immunosuppressants SNF3345 C and SNF4435 D featuring a tandem Stille coupling/electrocyclization cascade is described.
"Endo" and "Exo" Bicyclo[4.2.0]-octadiene Isomers from the Electrocyclization of Fully Substituted Tetraene Models for SNF 4435C and D. Control of Stereochemistry by Choice of a Functionalized Substituent
Parker, Kathlyn A.,Lim, Yeon-Hee
, p. 161 - 164 (2007/10/03)
(Matrix presented) A tandem electrocyclic closure, perceived as the key step in a biomimetic approach to SNF 4435C and D, was tested with 1,1,8-trisubstituted tetraene substrates. The ratio of endo:exo products could be controlled by the choice of the Rs
