444784-45-6

Basic information

• Product Name: 4-{[4-(2,4-dichloro-phenoxy)-but-2-ynyl]-methyl-amino}-chromen-2-one
• CAS NO: 444784-45-6
• Molecular Weight: 388.25
• Mol File: 444784-45-6.mol

Chemical Properties

• CAS DataBase Reference: 4-{[4-(2,4-dichloro-phenoxy)-but-2-ynyl]-methyl-amino}-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{[4-(2,4-dichloro-phenoxy)-but-2-ynyl]-methyl-amino}-chromen-2-one(444784-45-6)
• EPA Substance Registry System: 4-{[4-(2,4-dichloro-phenoxy)-but-2-ynyl]-methyl-amino}-chromen-2-one(444784-45-6)

Safety Data

• Hazardous Substances Data: 444784-45-6(Hazardous Substances Data)

Upstream product

• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 200055-89-6 4-(4-toluenesulfonyloxy)coumarin 
• 417726-12-6 1-(2,4-dichlorophenoxy)-4-N-methylaminobut-2-yne 

Relevant articles and documents

Synthesis of bioactive heterocycles: Tandem reaction of 4-N-(4′-aryloxybut-2′-ynyl),N-methylaminocoumarin with 3-chloroperoxybenzoic acid

A number of 4-N-(4′-aryloxybut-2′-ynyl),N-methylaminocoumarins (4a-e) on treatment with one equivalent of 3-chloroperoxybenzoic acid at 0-5°C for 10 min and then stirring at rt for 10 h afforded pyrrolo[3,2-c]coumarin derivatives in 70-75% yields. The 4-N-(4′-aryloxybut-2′-ynyl),N-methylaminocoumarins 4a-e were in turn prepared from 4-tosyloxycoumarin (2) and (4-aryloxybut-2-ynyl)-N-methylamine (3a-e).