444788-52-7

Basic information

• Product Name: 1-(4-benzoyloxybutyloxymethyl)-6-(3,5-dimethylbenzyl)-5-ethyluracil
• Synonyms: 1-(4-benzoyloxybutyloxymethyl)-6-(3,5-dimethylbenzyl)-5-ethyluracil
• CAS NO: 444788-52-7
• Molecular Weight: 464.561
• Mol File: 444788-52-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-benzoyloxybutyloxymethyl)-6-(3,5-dimethylbenzyl)-5-ethyluracil(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-benzoyloxybutyloxymethyl)-6-(3,5-dimethylbenzyl)-5-ethyluracil(444788-52-7)
• EPA Substance Registry System: 1-(4-benzoyloxybutyloxymethyl)-6-(3,5-dimethylbenzyl)-5-ethyluracil(444788-52-7)

Safety Data

• Hazardous Substances Data: 444788-52-7(Hazardous Substances Data)

Upstream product

• 32651-37-9 4-benzoyloxybutan-1-ol 
• 50-00-0 formaldehyd 
• 171048-65-0 6-(3,5-dimethylbenzyl)-5-ethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 

Relevant articles and documents

Pyrimidine acyclonucleoside derivatives, preparation method and use thereof

The invention relates to a compound having general formula (I): wherein n is equal to 3; R1 is an ethyl or isopropyl group; each of the R2 groups is independently of each other a hydrogen atom, a C1-C3 alkyl group or a halogen atom; one of the R3 and R4 groups represents a hydrogen atom while the other of the R3 and R4 groups represents an OH or OR5 group, where R5 can be a C2-C7 acyl group, an alkyl(C1-C6)animo-carbonyl group, an aralkyl(C1-C6)aminocarbonyl optionally substituted on the aryl, an arylcarbonyl group optionally substituted or a heteroarylaminocarbonyl group. Said compound is particularly suitable as an antiviral agent and especially as an anti-HIV-1 agent.