444892-80-2 Usage
General Description
The chemical "2-(4-BOC-PIPERAZINYL)-2-(2-FLUORO-PHENYL)ACETIC ACID" is a compound with a piperazine ring and a fluorophenyl acetic acid moiety. It is commonly used in medicinal chemistry, specifically in the development of pharmaceuticals. The BOC (tert-butyloxycarbonyl) protecting group is often used to protect the amine functional group of piperazine, allowing for selective reactions at other sites within the molecule. The presence of the fluorophenyl acetic acid group suggests potential anti-inflammatory or analgesic properties. Overall, this compound is important in synthetic organic chemistry and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 444892-80-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,4,8,9 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 444892-80:
(8*4)+(7*4)+(6*4)+(5*8)+(4*9)+(3*2)+(2*8)+(1*0)=182
182 % 10 = 2
So 444892-80-2 is a valid CAS Registry Number.
InChI:InChI=1/C17H23FN2O4/c1-17(2,3)24-16(23)20-10-8-19(9-11-20)14(15(21)22)12-6-4-5-7-13(12)18/h4-7,14H,8-11H2,1-3H3,(H,21,22)
444892-80-2Relevant articles and documents
Privileged structure based ligands for melanocortin receptors - Substituted benzylic piperazine derivatives
Fisher, Matthew J.,Backer, Ryan T.,Collado, Ivan,De Frutos, Oscar,Husain, Saba,Hsiung, Hansen M.,Kuklish, Steve L.,Mateo, Ana I.,Mullaney, Jeffrey T.,Ornstein, Paul L.,Paredes, Cristina Garcia,O'Brian, Thomas P.,Richardson, Timothy I.,Shah, Jikesh,Zgombick, John M.,Briner, Karin
, p. 4973 - 4978 (2007/10/03)
Replacement of the aryl piperazine moiety in compound 1 with a variety of substituted benzylic piperazines (6) yields compounds that afford melanocortin receptor 4 (MCR4) activity. Analogs with ortho substitution on the aromatic ring afforded the highest
