444892-80-2 Usage
Uses
Used in Pharmaceutical Development:
2-(4-BOC-PIPERAZINYL)-2-(2-FLUORO-PHENYL)ACETIC ACID is used as a key intermediate in the synthesis of various pharmaceuticals for its potential anti-inflammatory or analgesic properties. The BOC protecting group allows for the selective functionalization of the molecule, which is crucial for the development of new drugs with improved efficacy and reduced side effects.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2-(4-BOC-PIPERAZINYL)-2-(2-FLUORO-PHENYL)ACETIC ACID serves as a valuable compound for studying the structure-activity relationships of potential drug candidates. Its unique structural features, including the piperazine ring and the fluorophenyl acetic acid moiety, provide a foundation for exploring novel therapeutic agents with enhanced pharmacological profiles.
Used in Organic Synthesis:
2-(4-BOC-PIPERAZINYL)-2-(2-FLUORO-PHENYL)ACETIC ACID is also utilized in organic synthesis as a building block for creating more complex molecules with diverse applications. The presence of the BOC group and the fluorophenyl acetic acid functionality makes it a versatile starting material for the preparation of a wide range of organic compounds, including those with potential applications in material science, agrochemicals, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 444892-80-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,4,8,9 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 444892-80:
(8*4)+(7*4)+(6*4)+(5*8)+(4*9)+(3*2)+(2*8)+(1*0)=182
182 % 10 = 2
So 444892-80-2 is a valid CAS Registry Number.
InChI:InChI=1/C17H23FN2O4/c1-17(2,3)24-16(23)20-10-8-19(9-11-20)14(15(21)22)12-6-4-5-7-13(12)18/h4-7,14H,8-11H2,1-3H3,(H,21,22)
444892-80-2Relevant academic research and scientific papers
Privileged structure based ligands for melanocortin receptors - Substituted benzylic piperazine derivatives
Fisher, Matthew J.,Backer, Ryan T.,Collado, Ivan,De Frutos, Oscar,Husain, Saba,Hsiung, Hansen M.,Kuklish, Steve L.,Mateo, Ana I.,Mullaney, Jeffrey T.,Ornstein, Paul L.,Paredes, Cristina Garcia,O'Brian, Thomas P.,Richardson, Timothy I.,Shah, Jikesh,Zgombick, John M.,Briner, Karin
, p. 4973 - 4978 (2007/10/03)
Replacement of the aryl piperazine moiety in compound 1 with a variety of substituted benzylic piperazines (6) yields compounds that afford melanocortin receptor 4 (MCR4) activity. Analogs with ortho substitution on the aromatic ring afforded the highest
