584-74-7

Basic information

• Product Name: ETHYL 2-FLUOROPHENYLACETATE
• Synonyms: ETHYL 2-FLUOROPHENYLACETATE;Ethyl 2-fluorophenylacetate 99%;2-Fluorophenylacetic acid ethyl ester;Ethyl 2-(2-fluorophenyl)acetate;2-Fluorophenylacetic acid ethyl ester, Ethyl (2-fluorophenyl)acetate;Ethyl2-fluorophenylacetate99%;Ethyl 2-(2-fluorophenyl)
• CAS NO: 584-74-7
• Molecular Formula: C₁₀H₁₁FO₂
• Molecular Weight: 182.19
• Mol File: 584-74-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 235°C
• Flash Point: 85°C
• Appearance: /
• Density: 1,101 g/cm3
• Vapor Pressure: 0.0819mmHg at 25°C
• Refractive Index: 1.4810
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: ETHYL 2-FLUOROPHENYLACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-FLUOROPHENYLACETATE(584-74-7)
• EPA Substance Registry System: ETHYL 2-FLUOROPHENYLACETATE(584-74-7)

Safety Data

• Statements: 36/38
• Safety Statements: 26-36
• Hazardous Substances Data: 584-74-7(Hazardous Substances Data)

Usage

General Description

Ethyl 2-fluorophenylacetate is a chemical compound with the molecular formula C11H11FO2. This substance belongs to the group of organic compounds known as phenylpropanoids and polyketides, which are natural or synthetically produced compounds with a wide range of biological activities and functions. Ethyl 2-fluorophenylacetate is characterized by an aromatic structure with a fluorine atom and an ester group present. It is commonly used in the synthesis of various pharmaceuticals and other organic compounds. Despite its extensive use, data regarding its toxicity and environmental effects are relatively limited, necessitating proper handling and disposal guidelines to ensure safety.

InChI:InChI=1/C10H11FO2/c1-2-13-10(12)7-8-5-3-4-6-9(8)11/h3-6H,2,7H2,1H3

Upstream product

• 64-17-5 ethanol 
• 451-82-1 (2-fluorophenyl)acetic acid 
• 1993-03-9 o-fluorophenylboronic acid 
• 105-36-2 ethyl bromoacetate 
• 326-62-5 2-fluorophenyl acetonitrile 
• 101-97-3 Ethyl 2-phenylethanoate 
• 20511-20-0 ethyl p-methylcinnamate 
• 326-63-6 2-(2-fluorophenyl)acetamide 
• 6048-06-2 ethyl-p-chlorocinnamate 
• 103-36-6 ethyl 3-phenyl-2-propenoate 

Downstream Products

• 50919-06-7 2-(2-fluorophenyl)ethanol 
• 405196-39-6 2-(2-fluorophenyl)pentanedioic acid 5-(1,1-dimethylethyl)-1-ethyl ester 
• 849690-59-1 5-(2-fluoro-phenyl)-3-(2-nitro-phenyl)-2,3-dihydro-[1,2,3]triazol-4-one 
• 150322-73-9 1-cyclopropyl-2-(2-fluorophenyl)ethanone 
• 1613403-38-5 ethyl 2-diazo-2-(2-fluorophenyl)acetate 
• 1613403-70-5 (2E,4E)-ethyl 2-(2-fluorophenyl)-5-(4-methoxyphenyl)penta-2,4-dienoate 
• 1215910-00-1 2-cyclopentyl-2-(2-fluorophenyl)acetic acid 

Relevant articles and documents

2-(Halogenated Phenyl) acetamides and propanamides as potent TRPV1 antagonists

A series consisting of 117 2-(halogenated phenyl) acetamide and propanamide analogs were investigated as TRPV1 antagonists. The structure–activity analysis targeting their three pharmacophoric regions indicated that halogenated phenyl A-region analogs exhibited a broad functional profile ranging from agonism to antagonism. Among the compounds, antagonists 28 and 92 exhibited potent antagonism toward capsaicin for hTRPV1 with Ki[CAP] = 2.6 and 6.9 nM, respectively. Further, antagonist 92 displayed promising analgesic activity in vivo in both phases of the formalin mouse pain model. A molecular modeling study of 92 indicated that the two fluoro groups in the A-region made hydrophobic interactions with the receptor.

Imidazole and Triazole Compounds, Their Use and Agents Containing The Same

The present invention relates to compounds of the formula I in which the variables have the meanings defined in the claims and in the description.

PYRROLIDINE INHIBITORS OF IAP

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