444911-56-2

Upstream product

• 189996-60-9 2,3-O-isopropylidene-D-erythrose 
• 622-30-0 N-benzyl hydroxylalmine 
• 444911-54-0 (3aR,4R,6aR)-N-benzyl-tetrahydro-N-hydroxy-2,2-dimethylfuro[3,4-d]-1,3-dioxol-4-amine 

Downstream Products

• 845817-23-4 1,2,3,4-tetradeoxy-4-{hydroxy[(1S)-1-phenylbut-3-enyl]amino}-5,6-O-(1-methylethylidene)-D-ribo-hept-1-enitol 
• 845817-26-7 1,2,3-trideoxy-3-{hydroxy[(1R)-1-phenylprop-2-ynyl]amino}-4,5-O-(1-methylethylidene)-D-ribo-hex-1-ynitol 
• 1022910-87-7 C₂₀H₂₃NO₄ 
• 845817-30-3 1,2,3,4-tetradeoxy-4-{acetyloxy[(1S)-1-phenylbut-3-enyl]amino}-5,6-O-(1-methylethylidene)-D-ribo-hept-1-enitol 
• 845817-28-9 6-O-acetyl-3-{(acetyloxy)[(1R)-1-phenylprop-2-enyl]amino}-1,2,3-trideoxy-4,5-O-(1-methylethylidene)-D-ribo-hex-1-enitol 
• 845817-31-4 {(4R,5S)-5-[(2S,7S)-1-(acetyloxy)-7-phenyl-2,3,6,7-tetrahydro-1H-azepin-2-yl]-2,2-dimethyl-1,3-dioxolan-4-yl}methanol 
• 845817-32-5 (2S,7S)-2-[(4S,5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-7-phenyl-2,3,6,7-tetrahydro-1H-azepin-1-ol 
• 845817-33-6 {(4R,5S)-2,2-dimethyl-5-[(2S,7S)-7-phenyl-2,3,6,7-tetrahydro-1H-azepin-2-yl]-1,3-dioxolan-4-yl}methanol 
• 845817-34-7 (3aR,6S,10aS,10bS)-2,2-dimethyl-6-phenyl-3a,6,7,10,10a,10b-hexahydro-4H-[1,3]dioxolo[3,4]pyrrolo[1,2-a]azepine 

Relevant academic research and scientific papers

Manganese dioxide oxidation of hydroxylamines to nitrones

Several structurally differentiated N,N-dialkylhydroxylamines were oxidised to the corresponding nitrones using MnO2. Manganese dioxide revealed an efficient and mild reagent for oxidation of hydroxylamines, showing a level of regioselectivity

Preparation of N-Glycosylhydroxylamines and Their Oxidation to Nitrones for the Enantioselective Synthesis of Isoxazolidines

N-benzyl- and N-methyl-N-glycosylhydroxylamines 3a-i were conveniently obtained by reaction of sugars with N-substituted hydroxylamines according to a novel procedure. Subsequent oxidation occurred at the alkyl group, selectively affording the correspondi

Practical synthesis of N-alkyl-N-glycosylhydroxylamines, multitalented precursors of enantiomerically pure nitrones

A practical synthesis of N-benzyl-N-glycosylhydroxylamines 3 (R=CH2Ph) is reported. The ability of these compounds to act as versatile synthetic intermediates is demonstrated by their oxidation followed by cycloaddition to N-glycosyl isoxazolidines and by the novel direct cycloaddition as masked acyclic, highly functionalized chiral nitrones.