4450-97-9Relevant academic research and scientific papers
A facile synthesis of pyrrolidine-based iminosugars as potential alpha-glucosidase inhibitors
Bacho, Muhamad Zulfaqar,Hamzah, Ahmad Sazali,Kamarulzaman, Firdaus,Mohammat, Mohd Fazli,Shaameri, Zurina,Wibowo, Agustono
, p. 309 - 319 (2020/07/03)
A multifaceted approach comprising MCR (multicomponent reaction), amination and stereoselective reduction reactions was used to synthesize new pyrrolidine-based iminosugars. The key step of this strategy involves the contruction of a highly functionalised
NOVEL PYRAZOLO-PYRROLO-PYRIMIDINE-DIONE DERIVATIVES AS P2X3 INHIBITORS
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Page/Page column 133, (2019/05/15)
The present invention covers substituted Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R1, R2 and R3 are as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.
