445018-46-2Relevant academic research and scientific papers
Orthogonal N,N-deprotection strategies of β-amino esters
Bull, Steven D.,Davies, Stephen G.,Kelly, Peter M.,Gianotti, Massimo,Smith, Andrew D.
, p. 3106 - 3111 (2007/10/03)
β-Amino esters derived from the stereoselective conjugate addition of homochiral lithium N-benzyl-N-α-methyl-4-methoxybenzylamide to α,β-unsaturated esters may be orthogonally mono-N-deprotected under either oxidative or acid-promoted reaction conditions. Further oxidative deprotection affordsβ-amino acids or β-lactams.
