445224-49-7Relevant academic research and scientific papers
Rh-Catalyzed aldehydic C-H alkynylation and annulation
Ramakrishna, Boddu S.,Rao, Maddali L. N.
, p. 1402 - 1411 (2020)
Novel Rh-catalyzed aldehydic C-H bond alkynylation and annulation for the in situ synthesis of chromones and aurones are described. It involves the sequential aldehyde C-H bond alkynylation of salicylaldehyde with in situ generated 1-bromoalkyne from 1,1-
Construction of the flavones and aurones through regioselective carbonylative annulation of 2-bromophenols and terminal alkynes
Liu, Jianming,Liu, Muwen,Yue, Yuanyuan,Zhang, Ningfei,Zhang, Yuanli,Zhuo, Kelei
supporting information, p. 1802 - 1807 (2013/04/24)
The easily available and efficient catalyst containing a benzimidazolium ligand and PdCl2(PPh3)2 demonstrated excellent catalytic activity to construct the flavones and aurones, respectively. This reaction can be operated under mild conditions, affording the desired products in moderate to good yields. This protocol was used to prepare the flavones and aurones by a slight modification of amines.
