445307-04-0Relevant academic research and scientific papers
Tandem silylformylation-allyl(crotyl)silylation: A new approach to polyketide synthesis
Zacuto, Michael J.,O'Malley, Steven J.,Leighton, James L.
, p. 8889 - 8900 (2003)
Tandem intramolecular silylformylation-allyl(crotyl)silylation reactions have been developed that allow the highly efficient synthesis of polyketide fragments. The substrates are subjected to Rh(I)-catalyzed silylformylation to afford β-(diallyl)silyl ald
Tandem intramolecular silylformylation-crotylsilylation: Highly efficient synthesis of polyketide fragments
Zacuto, Michael J.,O'Malley, Steven J.,Leighton, James L.
, p. 7890 - 7891 (2002)
Polyketide fragments may be rapidly and efficiently assembled in the tandem intramolecular silylformylation-crotylsilylation of alkenes and alkynes. The reactions establish up to three new stereocenters with good-to-excellent diastereoselectivity, and the
