445486-63-5Relevant academic research and scientific papers
Extending the scope of a known furan synthesis - A novel route to 1,2,4-trisubstituted pyrroles
Friedrich, Marko,W?chtler, Andreas,De Meijere, Armin
, p. 619 - 621 (2002)
2-(Acylmethylene)propanediol diacetates, which cyclize readily under acidic conditions to give furans (76-84%) react with primary amines under palladium catalysis to give 1,2,4-trisubstituted pyrroles in moderate to good yields (39-53%). When glycine meth
