446021-73-4 Usage
Description
(Rs)-2,4,6-trimethylbenzenesulfinamide, also known as Toluenesulfinamide, is a compound belonging to the class of sulfinamides, which are organic compounds containing a sulfinyl group attached to an amine. It is an odorless, white to slightly yellow crystalline solid that is soluble in most organic solvents. This chemical is recognized for its pharmacological activities, including antiviral and antineoplastic properties, making it a valuable asset in medicinal chemistry research.
Uses
Used in Pharmaceutical Industry:
(Rs)-2,4,6-trimethylbenzenesulfinamide is used as a reagent for the synthesis of various organic compounds, particularly in the pharmaceutical industry. Its role in the synthesis process is crucial due to its ability to facilitate the creation of new medicinal compounds.
Used in Medicinal Chemistry Research:
(Rs)-2,4,6-trimethylbenzenesulfinamide is used as a research compound for exploring its antiviral and antineoplastic properties. These pharmacological activities make it a promising candidate for the development of new treatments for viral infections and cancer.
Used in Pesticide and Herbicide Synthesis:
(Rs)-2,4,6-trimethylbenzenesulfinamide is used as a key intermediate in the synthesis of certain pesticides and herbicides. Its involvement in the production of these agricultural chemicals highlights its versatility and importance in different sectors.
Safety Measures:
Despite its potential applications, the use and handling of (Rs)-2,4,6-trimethylbenzenesulfinamide require caution and appropriate safety measures. It is essential to avoid skin and eye contact, as the compound can cause irritation upon contact. Proper protective equipment and handling procedures should be followed to minimize risks associated with its use.
Check Digit Verification of cas no
The CAS Registry Mumber 446021-73-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,6,0,2 and 1 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 446021-73:
(8*4)+(7*4)+(6*6)+(5*0)+(4*2)+(3*1)+(2*7)+(1*3)=124
124 % 10 = 4
So 446021-73-4 is a valid CAS Registry Number.
446021-73-4Relevant articles and documents
Asymmetric synthesis of sulfinamides using (-)-quinine as chiral auxiliary
Zhang, Yongda,Chitale, Sampada,Goyal, Navneet,Li, Guisheng,Han, Zhengxu S.,Shen, Sherry,Ma, Shengli,Grinberg, Nelu,Lee, Heewon,Lu, Bruce Z.,Senanayake, Chris H.
, p. 690 - 695 (2012/02/16)
A process has been designed and demonstrated for the asymmetric synthesis of sulfinamides using quinine as auxiliary. A variety of chiral sulfinamides including N-alkyl sulfinamides with diverse structure were prepared in good yields and excellent enantioselectivity starting from easily available and inexpensive reagents. The auxiliary quinine could be recovered and recycled.
Convenient synthesis of chiral non-racemic S-mesityl sulfinimines
Sasraku-Neequaye, Leonid,MacPherson, David,Stockman, Robert A.
, p. 1129 - 1132 (2008/09/18)
A direct multi-component coupling of (2S,4R,5S)-N-tosyl-4-methyl-5-phenyl-1,2,3-oxathiozolidine-2-oxide with mesityl magnesium bromide, LHMDS and a range of aldehydes produces chiral sulfinimines in essentially optically pure form in an operationally simp
Application of P,N-Sulfinyl Imine Ligands to Iridium-Catalyzed Asymmetric Hydrogenation of Olefins
Schenkel, Laurie B.,Ellman, Jonathan A.
, p. 1800 - 1802 (2007/10/03)
The utility of a novel class of P,N-ligands incorporating a chiral sulfinyl imine moiety is demonstrated in the iridium-catalyzed hydrogenation of both functionalized and unfunctionalized olefins, in which enantioselectivities of up to 94% are achieved. T
