446069-87-0Relevant articles and documents
Identification of potent and novel α4β1 antagonists using in silico screening
Singh, Juswinder,Abraham, William M.,Adams, Steven P.,Van Vlijmen, Herman,Liao, Yusheng,Lee, Wen-Cherng,Cornebise, Mark,Harris, Mary,Shu, I-Hsiang,Gill, Alan,Cuervo, Julio H.
, p. 2988 - 2993 (2007/10/03)
The antigen α4β1 (very late antigen-4, VLA-4) plays an important role in the migration of white blood cells to sites of inflammation. It has been implicated in the pathology of a variety of diseases including asthma, multiple sclerosis, and rheumatoid art