446284-46-4

Usage

Uses

Used in Medicinal Chemistry:
1H-Pyrrolo[2,3-c]pyridine-7-carboxaldehyde,4-fluoro-(9CI) is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its heterocyclic structure allows for the development of new drugs with improved biological activity and pharmacokinetic properties.
Used in Drug Discovery:
1H-Pyrrolo[2,3-c]pyridine-7-carboxaldehyde,4-fluoro-(9CI) is used as a potential lead compound in drug discovery. The addition of a fluorine atom to the molecule can enhance its biological activity, making it a promising candidate for the development of new therapeutic agents.
Used in Organic Synthesis:
1H-Pyrrolo[2,3-c]pyridine-7-carboxaldehyde,4-fluoro-(9CI) is used as a versatile building block in organic synthesis. Its unique structure allows for the creation of a wide range of chemical compounds with diverse applications in various industries.

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 136888-20-5 5-fluoro-2-hydroxy-3-nitropyridine 
• 446284-38-4 7-bromo-4-fluoro-1H-pyrrolo[2,3-c]pyridine 
• 51173-05-8 5-fluoropyridin-2-ol 
• 51173-04-7 5-fluoro-2-methoxypyridine 
• 6628-77-9 6-methoxy-pyridin-3-ylamine 

Downstream Products

• 446290-68-2 C₂₃H₁₈FN₅O₄ 

Relevant academic research and scientific papers

Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 12. Structure-activity relationships associated with 4-fluoro-6-azaindole derivatives leading to the identification of 1-(4-benzoylpiperazin-1-yl)-2-(4- fluoro-7-[1,2,3]triazol-1-yl-1H-

A series of highly potent HIV-1 attachment inhibitors with 4-fluoro-6-azaindole core heterocycles that target the viral envelope protein gp120 has been prepared. Substitution in the 7-position of the azaindole core with amides (12a,b), C-linked heterocycl

Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives

This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.