446312-37-4

Upstream product

• 934231-06-8 4-(3-iodo-5-isopropyl-4-methoxymethoxy-benzyl)-3,5-dimethyl-phenol 
• 863639-45-6 methyl 2-(4-(4-hydroxy-3-isopropylbenzyl)-3,5-dimethylphenoxy)acetate 
• 328236-46-0 3,5-dimethyl-4-(3'-isopropyl-4'-O-methoxymethylbenzyl)-O-triisopropylsilylphenol 
• 328236-47-1 3,5-dimethyl-4-(3'-isopropyl-4'-O-methoxymethylbenzyl)phenol 
• 851227-20-8 [4-(3-isopropyl-4-methoxymethoxybenzyl)-3,5-dimethylphenoxy]acetic acid methyl ester 

Downstream Products

• 863640-46-4 {4-[3-(4-azido-phenylethynyl)-4-hydroxy-5-isopropyl-benzyl]-3,5-dimethyl-phenoxy}-acetic acid methyl ester 
• 446312-39-6 {4-[4-hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl]-3,5-dimethylphenoxy}acetic acid methyl ester 
• 863640-39-5 {4-[3-(4-azido-phenylethynyl)-5-isopropyl-4-methoxymethoxy-benzyl]-3,5-dimethyl-phenoxy}-acetic acid methyl ester 
• 446312-38-5 {4-[3-isopropyl-4-methoxymethoxy-5-(4-nitrophenylethynyl)benzyl]-3,5-dimethylphenoxy}acetic acid methyl ester 
• 446312-40-9 {4-[3-(4-aminophenylethynyl)-4-hydroxy-5-isopropylbenzyl]-3,5-dimethylphenoxy}acetic acid methyl ester 

Relevant academic research and scientific papers

Hammett analysis of selective thyroid hormone receptor modulators reveals structural and electronic requirements for hormone antagonists

Selective thyroid hormone modulators that function as isoform-selective agonists or antagonists of the thyroid hormone receptors (TRs) might be therapeutically useful in diseases associated with aberrant hormone signaling. The most potent thyroid hormone

Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment

Recent efforts have focused on the design and synthesis of thyroid hormone (T3) antagonists as potential therapeutic agents and chemical probes to understand hormone-signaling pathways. We previously reported the development of novel first-gene