4466-76-6

Usage

InChI:InChI=1/C19H12O/c20-12-15-11-14-10-9-13-5-1-2-7-17(13)19(14)18-8-4-3-6-16(15)18/h1-12H

Upstream product

• 112867-00-2 5-(ethoxycarbonyl)benzo[c]phenanthrene 
• 111273-70-2 5-(hydroxymethyl)benzo[c]phenanthrene 
• 4885-02-3 Dichloromethyl methyl ether 
• 195-19-7 benzo[c]phenathrene 

Downstream Products

• 858943-05-2 5-(β-phenylethenyl)benzo[c]phenanthrene 
• 858943-11-0 5-[β-(2-methoxyphenyl)ethenyl]benzo[c]phenanthrene 
• 196-52-1 dibenzo[c,p]chrysene 

Relevant academic research and scientific papers

Convenient syntheses of dibenzo[c,p]chrysene and its possible proximate and ultimate carcinogens: In vitro metabolism and DNA adduction studies

Dibenzo[c,p]chrysene (DB[c,p]C) is the only hexacyclic polycyclic aromatic hydrocarbon having two Cord regions, both in different chemical environments. Its environmental presence and relative tumorigenic potency are not known due to the lack of synthetic

2-[(arylmethyl)amino]-2-methyl-1,3-propanediol DNA intercalators. An examination of the effects of aromatic ring variation on antitumor activity and DNA binding

The effects of variation of aromatic ring size, shape, and side-chain position on antitumor activity and DNA binding in a series of carbocyclic 2-[(arylmethyl)amino]-2-methyl-1,3-propanediols (AMAPs) were examined. In general, the interaction of AMAPs wit

Carbocyclic derivatives

The present invention relates to compounds of formula (I) or a monomethyl or monoethyl ether thereof (the compound of formula (I) including these ethers may contain no more than 30 carbon atoms in total); ethers, esters, thereof; acid addition salts thereof; wherein Ar is a C15-18 fused tetracarbocyclic ring system containing 3 or 4 aromatic rings or a C17-22 fused pentacarbocyclic ring system containing 4 or 5 aromatic rings, or a substituted derivative thereof; the ring system Ar being planar or deviating only slightly from planarity. Thus, the ring system contains a maximum of two non-aromatic carbon atoms which may be in the same ring, in which case they are adjacent, or in different rings; Ar is not perylene, fluoranthene, chrysene, pyrene, or triphenylene; R1 contains not more than eight carbon atoms and is a group STR1 wherein m is 0 or 1; R5 is hydrogen; R6 and R7 are the same or different and each is hydrogen or C1-5 alkyl optionally substituted by hydroxy; R8 and R9 are the same or different and each is hydrogen or C1-3 alkyl; STR2 is a five- or six-membered saturated carbocyclic ring; R10 is hydrogen, methyl or hydroxymethyl; R11, R12 and R13 are the same or different and each is hydrogen or methyl; R14 is hydrogen, methyl, hydroxy or hydroxymethyl.

Carbocyclic derivatives

The present invention relates to compounds of formula (I) or a monomethyl or monoethyl ether thereof (the compound of formula (I) including these ethers may contain no more than 30 carbon atoms in total); ethers, esters, thereof; acid addition salts thereof; wherein Ar is a C15-18 fused tetracarbocyclic ring system containing 3 or 4 aromatic rings or a C17-22 fused pentacarbocyclic ring system containing 4, or 5 aromatic rings, or a substituted derivative thereof; the ring system Ar should be planar or deviate only slightly from planarity. Thus, the ring system contains a maximum of two non-aromatic carbon atoms which may be in the same ring, in which case they are adjacent, or in different rings; Ar is not perylene, fluoranthene, chrysene, pyrene, or triphenylene; R1 contains not more than eight carbon atoms and is a group STR1 wherein m is 0 or 1; R5 is hydrogen; R6 and R7 are the same or different and each is hydrogen or C1-5 alkyl optionally substituted by hydroxy; R8 and R9 are the same or different and each is hydrogen or C1-3 alkyl; STR2 is a five- or six-membered saturated carbocyclic ring; R10 is hydrogen, methyl or hydroxymethyl; R11, R12 and R13 are the same or different and each is hydrogen or methyl; R14 is hydrogen, methyl, hydroxy, or hydroxymethyl.