446855-45-4

Usage

Uses

Used in Pharmaceutical Industry:
[1,1'-Biphenyl]-4-carboxamide, N-[(4-chlorophenyl)methyl]is used as an intermediate compound for the synthesis of various pharmaceuticals. Its unique structural features, including the carboxamide and 4-chlorophenylmethyl groups, make it a valuable building block in the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic chemistry, [1,1'-Biphenyl]-4-carboxamide, N-[(4-chlorophenyl)methyl]serves as a reagent in multiple synthesis pathways. Its functional groups can be manipulated to produce a range of chemical products, contributing to the advancement of organic synthesis techniques and the creation of novel compounds with diverse applications.
Used in Research and Development:
[1,1'-Biphenyl]-4-carboxamide, N-[(4-chlorophenyl)methyl]is also utilized in research and development settings, where it can be explored for its potential properties and applications. Scientists may investigate its interactions with other molecules, its stability under various conditions, and its capacity to serve as a precursor to other valuable compounds. The findings from such research could lead to new discoveries and innovations in the chemical and pharmaceutical industries.

Upstream product

• 104-86-9 4-chlorobenzylamine 
• 92-92-2 biphenyl-4-carboxylic acid 

Relevant academic research and scientific papers

Synthesis, antifungal evaluation and in silico study of N-(4-halobenzyl)amides

A collection of 32 structurally related N-(4-halobenzyl)amides were synthesized from cinnamic and benzoic acids through coupling reactions with 4-halobenzylamines, using (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) as a c

Alpha-helical mimetics

Benzoyl urea derivatives that are alpha helical peptides mimetics that mimic BH3-only proteins, compositions containing them, their conjugation to cell-targeting-moieties, and their use in the regulation of cell death are disclosed. The benzoyl urea derivatives are capable of binding to and neutralizing pro-survival Bcl-2 proteins. Use of benzoyl urea derivatives in the treatment and/or prophylaxis of diseases or conditions associated with deregulation of cell death are also described.

ALPHA-HELICAL MIMETICS

Benzoyl urea derivatives that are alpha helical peptide mimetics that mimic BH3-only proteins, compositions containing them, their conjugation to cell-targeting moieties, and their use in the regulation of cell death are disclosed. The benzoyl urea derivatives are capable of binding to and neutralising pro-survival Bcl-2 proteins. Use of the benzoyl urea derivatives in the treatment and/or prophylaxis of diseases or conditions associated with deregulation of cell death are also disclosed.