447-14-3

Usage

Uses

Used in Pharmaceutical Industry:
1',2',2'-Trifluorostyrene is used as a key intermediate in the synthesis of pharmaceutical drugs, leveraging its unique structure and reactivity to produce a variety of medicinal compounds.
Used in Materials Industry:
1',2',2'-Trifluorostyrene is used as a monomer in the polymerization process to create a range of polymers with specific properties, such as enhanced thermal stability, chemical resistance, or mechanical strength. These polymers are then utilized in various applications across different industries, including automotive, aerospace, electronics, and consumer goods.
Used in Chemical Synthesis:
1',2',2'-Trifluorostyrene is used as a versatile building block in the synthesis of a wide array of chemicals, including specialty chemicals, agrochemicals, and advanced materials. Its reactivity and the presence of the trifluoromethyl group make it a valuable component in the development of new chemical entities with potential applications in various fields.

Upstream product

• 116-14-3 polytetrafluoroethylene 
• 591-51-5 phenyllithium 
• 79-38-9 Chlorotrifluoroethylene 
• 71-43-2 benzene 
• 591-50-4 iodobenzene 
• 811-97-2 1,1,1,2-tetrafluoroethane 
• 56424-23-8 α-phenyl-α,β,β,β-tetrafluoroethane 
• 74492-18-5 2-chloro-1-phenyl-1,2,2-trifluoroethane 
• 340-04-5 1-phenyl-2,2,2-trifluoromethylethanol 
• 384-67-8 2-chloro-2,2-difluoroacetophenone 
• 598-73-2 1-bromo-1,2,2-trifluoroethene 
• 98-80-6 phenylboronic acid 
• 5123-13-7 5,5-dimethyl-2-phenyl-1,3,2-dioxaborinane 
• 24388-23-6 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole 

Downstream Products

• 236736-28-0 hexafluoro-1,2-diphenylcyclobutane 
• 1423-78-5 4-Chlor-α,α'-difluor-stilben 
• 1735-38-2 α,α'-Difluor-4-bromstilben 
• 1737-02-6 1.2-Difluor-1-phenyl-propen-⁽¹⁾ 
• 15480-91-8 1,2-Difluor-1-phenyl-decen-⁽¹⁾ 
• 1423-75-2 α,α'-Difluor-2,4,6-trimethyl-stilben 
• 1993-42-6 1,4-Bis-(α,β-difluor-styryl)-benzol 
• 648-78-2 (1-Bromo-2-chloro-1,2,2-trifluoro-ethyl)-benzene 
• 40672-53-5 (2-Bromo-1-chloro-1,2,2-trifluoro-ethyl)-benzene 
• 40193-73-5 α,β-dichloro-α,β,β-trifluorostyrene 
• 40193-70-2 2-bromo-1,2,2-trifluoroethylbenzene 
• 91047-51-7 N-α,α,β-Trifluoro-β-phenylimidazole 
• 91047-56-2 N-α,α,β-Trifluoro-β-phenylethylbenzimidazole 
• 91047-57-3 1-(1,1,2-Trifluoro-2-phenylethyl)-2-methylbenzimidazole 

Relevant academic research and scientific papers

Solid-phase synthesis on functionalised fluoropolymer resins. Part 2: Preparation and properties of functional merrifieldtype resins possessing a perfluorinated polymer backbone

Monomers α,β,β-trifluorostyrene and 4-methyl-α,β,β- trifluorostyrene were prepared and were copolymerised under free-radical emulsion conditions to give highly stable, well defined lipophilic polymer resins. Benzylic halogenation of the polymer products gave 4-chloromethyl and 4-bromomethyl derivatives which could be elaborated through nucleophilic displacement of halide. The reaction of 4-fluorophenol with the 4- chloromethylated poly(trifluorostyrene) resin was followed by 1H and 19F NMR spectroscopy and proceeded more rapidly than for Merrifield resin. (C) 2000 Elsevier Science Ltd.

Synthesis method of aryl trifluoroethylene compound

The invention belongs to the technical field of chemical synthesis, and particularly relates to a synthesis method of an aryl trifluoroethylene compound, and the main improvement lies in that trifluoroethylene and aryl sulfinate are used as raw materials and react under the catalytic action of a transition metal salt to obtain the aryl trifluoroethylene compound. The selected arylation reagent is novel, the reaction condition is simple and mild, the cost is low, the operation is easy and convenient, the cost is low, the universality is wide, the environmental pollution is small and the atom economy is high, and industrial large-scale production is expected to be achieved.

Post-treatment method of trifluorostyrene synthesis liquid

The invention discloses a post-treatment method of a trifluorostyrene synthesis liquid. The method comprises: distilling a synthesis liquid, and rectifying the distillate to prepare trifluorostyrene.According to the invention, the method has the advantages of short post-treatment route, high yield and easiness in industrialization, and more importantly the solvent THF is easy to recover, so thatthe manufacturing cost of trifluorostyrene is favorably reduced, and industrial production is convenient to realize.

Solvent- A nd anion-dependent rearrangement of fluorinated carbene ligands provides access to fluorinated alkenes

The construction of fluorocarbene ligands within the coordination sphere of transition metal complexes using sequential nucleophilic and electrophilic addition to a vinylidene complex is described. Reaction of [Ru(η5-C5H5)(dppe)(CCPhF)][N(SO2Ph)2] with [NMe4]F results in nucleophilic attack of fluoride at the metal-bound carbon of the vinylidene ligand to give alkenyl complex [Ru(η5-C5H5)(dppe)(-CFCFPh)]. Subsequent eletrophilic fluorination with N-fluorobenzenesulfonimide (NFSI) results in the formation of the fluorinated carbene complex [Ru(η5-C5H5)(dppe)(CF-CHFPh)][N(SO2Ph)2]. The fluorocarbene complexes undergo rearrangement to liberate free fluorinated alkenes, a process governed by the choice of solvent and anion, representing a new metal-mediated route to fluorinated alkenes from alkynes.

The organic group is substituted with a fluorine-containing olefin production

PROBLEM TO BE SOLVED: To provide a production method that can produce a fluorine-containing olefin substituted with an organic group from a fluorine-containing olefin conveniently and efficiently (high yield, high selectivity, low cost).SOLUTION: The method for producing a fluorine-containing olefin substituted with an organic group includes a step of reacting a fluorine-containing olefin with an organosilicon compound in the presence of an organic transition metal catalyst containing a transition metal selected from among nickel, palladium, platinum, rhodium, ruthenium and cobalt.

Method for synthesizing trifluoroarylethene compounds

The invention relates to a method for synthesizing trifluoroarylethene compounds, belonging to the field of chemical synthesis. According to the method, trifluoroethylene is used as a starting raw material and reacts with easily available iodonium salts under proper conditions to produce the trifluoroarylethene compounds. Compared with traditional methods, the synthetic method provided by the invention has the characteristics of good universality, short reaction time, easy operation and the like; and since the synthetic method has the advantages of low cost, simple process, low pollution and the like, large-scale industrial production of the synthetic method can be realized.

Fluorinated Vinylsilanes from the Copper-Catalyzed Defluorosilylation of Fluoroalkene Feedstocks

Herein, a copper-catalyzed C?F bond defluorosilylation reaction of tetrafluoroethylene and other polyfluoroalkenes is described. Mechanistic studies, based on a series of stoichiometric reactions with copper complexes, revealed that the key steps of this defluorosilylation reaction are 1) the 1,2-addition of a silylcopper intermediate to the polyfluoroalkene and 2) a subsequent selective β-fluorine elimination, which generates a Cu?F species. The β-fluorine elimination is facilitated by Lewis acidic F?Bpin, which is generated in situ during the defluorosilylation.

A synthetic refrigeration working group ethylene group compound (by machine translation)

The invention relates to a synthetic refrigeration working group ethylene group compounds, is 1, 1 - dibromo - 1, 2, 2, 2 - tetrafluoroethane as raw materials, in under the action of the metal or metal compound, to obtain corresponding trifluorovinyl metal complex. This trifluoro vinyl metal complex in the catalyst and the like with the active substances under the action of the coupling reaction, containing the trifluoro ethylene group compound. The method of the invention easy availability of raw materials, the method is simple, the production safety, is a suitable for industrial production method. (by machine translation)

FLUORINE-CONTAINING COMPLEX COMPOUND AND METHOD FOR PRODUCING FLUORINE-CONTAINING ORGANIC COMPOUND USING FLUORINE-CONTAINING COMPLEX COMPOUND

PROBLEM TO BE SOLVED: To provide a fluorine-containing complex compound capable of synthesizing a fluorine-containing compound having organic groups at both terminals of a tetrafluoroethylene structure; and a method for producing and using the same. SOLUTION: There are provided: a method for producing [1] a fluorine-containing organic metal compound represented by the formula (1a): R1-CF2-CF2-M1 (1a) [M1 represents a metal selected from copper, zinc, nickel, iron, cobalt or tin and R1 represents an organic group] and [2] a fluorine-containing complex compound containing a ligand selected from a pyridine ring-containing compound or a phosphine, which comprises a step of reacting an organosilicon compound which is silicic acid having a moiety represented by the partial structural formula (2a): R1-Si, an ester thereof or a salt thereof with a hydroxide, a halide, an alkoxide, an aryloxide compound of a metal M1, a ligand and tetrafluoroethylene; and a fluorine-containing complex compound using the same. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

Α, β, β-trifluorolactic of industrial manufacturing method (by machine translation)

PROBLEM TO BE SOLVED: To provide a method of producing industrially α,β,β-trifluorostyrenes. SOLUTION: The method of producing industrially the α,β,β-trifluorostyrenes includes a dehydrofluorination step of reacting α-aryl-α,β,β,β-tetrafluoroethanes with an alkali metal-bis(trimethylsilyl) amide, in the production of α,β,β-trifluorostyrenes, and an after-treatment step executed followed thereto to react a mixture containing the α,β,β-trifluorostyrenes of objective products and bis-(trimethylsilyl) amine of a byproduct with hydrogen fluoride, or a salt or a complex comprising an organic base and hydrogen fluoride. COPYRIGHT: (C)2012,JPO&INPIT