447-47-2

Basic information

• Product Name: acetic acid-(2-amino-3-trifluoromethyl-anilide)
• Synonyms: acetic acid-(2-amino-3-trifluoromethyl-anilide)
• CAS NO: 447-47-2
• Molecular Weight: 218.178
• Mol File: 447-47-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: acetic acid-(2-amino-3-trifluoromethyl-anilide)(CAS DataBase Reference)
• NIST Chemistry Reference: acetic acid-(2-amino-3-trifluoromethyl-anilide)(447-47-2)
• EPA Substance Registry System: acetic acid-(2-amino-3-trifluoromethyl-anilide)(447-47-2)

Safety Data

• Hazardous Substances Data: 447-47-2(Hazardous Substances Data)

Upstream product

• 387-19-9 N-(2-nitro-3-(trifluoromethyl)phenyl)acetamide 

Downstream Products

• 384-32-7 2-methyl-4-(trifluoromethyl)-1H-benzo[d]imidazole 

Relevant articles and documents

1-(3-Aryloxyaryl)benzimidazole sulfones are liver X receptor agonists

A series of 1-(3-aryloxyaryl)benzimidazoles incorporating a sulfone substituent (6) was prepared. High affinity LXR ligands were identified (LXRβ binding IC50 values 10 nM), some with excellent agonist potency and efficacy in a functional assay of LXR activity measuring ABCA1 mRNA increases in human macrophage THP1 cells. The compounds were typically stable in liver microsome preparations and had good oral exposure in mice.