4473-26-1 Usage
Chemical structure
A purine derivative with two benzyl groups attached to the 1 and 9 positions of the purine ring.
Pharmacological applications
a. Potential inhibitor of dipeptidyl peptidase-4 (DPP-4) enzyme, which is involved in glucose metabolism regulation.
b. Possible antioxidant properties.
c. Potential anti-inflammatory properties.
Ongoing research
Further investigation into the biological activities and potential medical uses of 1,9-dibenzyl-1,9-dihydro-6H-purin-6-one is being conducted.
Check Digit Verification of cas no
The CAS Registry Mumber 4473-26-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,7 and 3 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4473-26:
(6*4)+(5*4)+(4*7)+(3*3)+(2*2)+(1*6)=91
91 % 10 = 1
So 4473-26-1 is a valid CAS Registry Number.
4473-26-1Relevant articles and documents
Biologically-validated HIV integrase inhibitors with nucleobase scaffolds: Structure, synthesis, chemical biology, molecular modeling, and antiviral activity
Nair, Vasu,Uchil, Vinod,Chi, Guochen,Dams, Iwona,Cox, Arthur,Seo, Byung
, p. 665 - 668 (2007)
Integrase, an enzyme of the pol gene of HIV, is a significant viral target for the discovery of anti-HIV agents. In this presentation, we report on the continuation of our work on the discovery of diketo acids, constructed on nucleobase scaffolds, that ar