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447406-78-2 Usage

Uses

Treatment of type 2 diabetes.

Brand name

GlaxoSmithKline.

Check Digit Verification of cas no

The CAS Registry Mumber 447406-78-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,7,4,0 and 6 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 447406-78:
(8*4)+(7*4)+(6*7)+(5*4)+(4*0)+(3*6)+(2*7)+(1*8)=162
162 % 10 = 2
So 447406-78-2 is a valid CAS Registry Number.

InChI:InChI=1/C23H21F4NO3S2/c1-12-9-15(6-8-18(12)31-22(3,4)21(29)30)32-11-19-13(2)28-20(33-19)16-7-5-14(10-17(16)24)23(25,26)27/h5-10H,11H2,1-4H3,(H,29,30)

447406-78-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	2-[4-[[2-[2-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]-2-methylpropanoic acid

1.2 Other means of identification

Product number	-
Other names	Sodelglitazar

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:447406-78-2 SDS

447406-78-2Upstream product

447406-78-2Downstream Products

447406-78-2Relevant academic research and scientific papers

Process development for sodelglitazar: A ppar panagonist

Brown, Andrew D.,Davis, Roman D.,Fitzgerald, Russ N.,Glover, Bobby N.,Harvey, Kim A.,Jones, Lynda A.,Liu, Bing,Patterson, Daniel E.,Sharp, Matthew J.

experimental part, p. 297 - 302 (2010/04/22)

Three efficient syntheses of sodelglitazar (1) have been developed. In particular, the third synthesis avoids the use of zinc and eliminates the resulting heavy metal waste stream as well as the potential genotoxic methanesulfonate in the two earlier syntheses. This process produces sodelglitazar in 74% overall yield from readily available thiophenol (8) and thiazole alcohol (3).

Thiazole derivatives for treating ppar related disorders

-

, (2008/06/13)

The present invention provides compounds of formula (I). These compounds are used for the treatment of PPAR related diseases.

PROCESS FOR PREPARATION OF CHEMICAL COMPOUNDS

-

Page/Page column 40-42, (2010/02/07)

The present invention relates to a process for the preparation of certain chemical compounds. In particular, the present invention relates to a method for the preparation of compounds that have been shown to activate human peroxisome proliferator activate

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