44742-89-4

Basic information

• Product Name: Ammonium hydrogen maleate
• Synonyms: ammonium hydrogen maleate;Maleic acid monoammonium salt;(Z)-2-Butenedioic acid hydrogen 1-ammonium salt;Maleic acid 1-ammonium salt
• CAS NO: 44742-89-4
• Molecular Formula: C₄H₄O₄*H₃N
• Molecular Weight: 133.1
• EINECS: 256-163-5
• Mol File: 44742-89-4.mol

Chemical Properties

• Boiling Point: 400.7 °C at 760 mmHg
• Flash Point: 196.1 °C
• Appearance: /
• Vapor Pressure: 5.19E-06mmHg at 25°C
• CAS DataBase Reference: Ammonium hydrogen maleate(CAS DataBase Reference)
• NIST Chemistry Reference: Ammonium hydrogen maleate(44742-89-4)
• EPA Substance Registry System: Ammonium hydrogen maleate(44742-89-4)

Safety Data

• Hazardous Substances Data: 44742-89-4(Hazardous Substances Data)

Usage

Uses

Used in Food Industry:
Ammonium hydrogen maleate is used as a buffering agent for maintaining the pH levels in various food products, ensuring the stability and quality of the final product.
Used in Pharmaceutical Industry:
Ammonium hydrogen maleate is used as a chelating agent for binding metal ions in pharmaceutical formulations, which can improve the solubility and bioavailability of certain drugs.
Used in Organic Synthesis:
Ammonium hydrogen maleate is used as a starting material or intermediate in the synthesis of various organic compounds, contributing to the development of new chemical entities and products.
Safety Precautions:
Despite its prevalent use, safety precautions should be observed as ammonium hydrogen maleate can cause irritation when it comes in contact with the skin or eyes, or if ingested or inhaled. Proper handling and storage measures should be implemented to minimize the risk of exposure.

InChI:InChI=1/C4H4O4.H3N/c5-3(6)1-2-4(7)8;/h1-2H,(H,5,6)(H,7,8);1H3/b2-1-;

Upstream product

• 39689-00-4 5-azido-2-furanecarbaldehyde 
• 110-17-8 (2E)-but-2-enedioic acid 
• 110-16-7 maleic acid 

Downstream Products

• 110-17-8 (2E)-but-2-enedioic acid 
• 56-84-8 L-Aspartic acid 
• 617-45-8 aspartic Acid 
• 105-75-9 dibutyl fumarate 

Relevant articles and documents

Preparation method of organic metal salt additive (by machine translation)

The organic metal salt additive, prepared by mixing :(1), washing, with short-chain organic acid as acid source, and then mixing, with the resulting solution of Step ;(2) to obtain the high-purity organic metal salt additive, has the advantages (1) as follows, The organic metal salt additive is relatively high in crystal form structure and high in purity, and has good industrial application prospects, through mixing, of an iron source or a calcium source, or a, zinc source with a high-purity, organic metal salt additive agent in an aqueous solution with, a wide,price. product source. (by machine translation)

METHOD FOR PREPARING AMMONIUM SALTS OF FUMARIC OR SUCCINIC ACID

An improved process for preparing ammonium salts from fumaric or succinic acid, is described. The method consists of neutralizing the corresponding acid carbonate or ammonium bicarbonate at a molar stoichiometric or greater than the stoichiometric ratio of 4-5% in a saturated aqueous solution of the synthesized salt at a temperature not exceeding 40° C., followed by separation of the product and drying at a temperature not exceeding 70° C. After separation of the ammonium salts, the filtrate can be re-used. Isolation of the product is usually carried out by cooling the reaction mixture to a temperature of 15-18C°. The product comes out in almost crystalline form. Saturated aqueous solution of the synthesized salt is formed by the interaction of carbonate or ammonium bicarbonate with the appropriate acid at a temperature not exceeding 40° C. It is possible to obtain cleaner salt concentration weighing more than 99% and not yielding lower than 98%. The method allows for an increase in the yield of targeted products and ensures their consistent high quality due to their formation in crystalline form.

PROCESSES FOR PRODUCING NH4+ -OOC-R-COOH COMPOUNDS FROM FERMENTATION BROTHS CONTAINING NH4+ -OOC-R-COO-NH4+COMPOUNDS AND/OR HOOC-R-COOH COMPOUND ACIDS, AND CONVERSION OF NH4+ -OOC-R-COOH COMPOUNDS TO HOOC-R-COOH COMPOUND ACIDS

A process for making a NH4+ OOC-R-COOH compound from a clarified NH4+ OOC- R-COO' NH4+ compound-containing fermentation broth includes (a) distilling the broth to form an overhead that includes water and ammonia, and a liquid bottoms that includes a NH4+ OOC~R~COOH compound, at least some of a NH4+ QOC-R-COO" NH4+ compound, and at least about 20 wt% water; (b) cooling the bottoms to a temperature sufficient to cause the bottoms to separate into a NH4+ OOC-R~C00' NH4+ compound-containing liquid portion in contact with a NH4+ OOC-R-COOH compoond-containing solid portion that is substantially free of the NH4+ OOC-R-COO" NH4+compound; (c) separating the solid portion from the liquid portion; and (d) recovering the solid portion.

Opening of the Furan Ring in 5-Azido-2-furaldehyde

Fission of the furan ring in 5-azido-2-furaldehyde is described. α-Furylnitrene, formed from α-azido furan derivatives, is stabilized by the furan ring fission.Transformation of the intermediate to quinoxaline and pyrazole derivatives is also studied.