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(s,s)-2-ALLYL-2-CHLORO-3,4-DIMETHYL-5-PHENYL-[1,3,2]-OXAZASILOLIDINE is a complex organic compound belonging to the class of strained silacycles. It is characterized by its unique structure, which includes a silicon atom and an oxygen atom in a six-membered ring, along with a chloro and allyl group. (s,s)-2-ALLYL-2-CHLORO-3,4-DIMETHYL-5-PHENYL-[1,3,2]-OXAZASILOLIDINE is known for its potential applications in various chemical reactions and processes due to its strained nature and reactivity.

447440-43-9

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447440-43-9 Usage

Uses

1. Enantioselective Allylation Reagents:
(s,s)-2-ALLYL-2-CHLORO-3,4-DIMETHYL-5-PHENYL-[1,3,2]-OXAZASILOLIDINE is used as a powerful enantioselective allylation reagent for the synthesis of various chiral compounds. Its unique structure allows for high selectivity in reactions, making it a valuable tool in the field of asymmetric synthesis.
Used in Pharmaceutical Industry:
(s,s)-2-ALLYL-2-CHLORO-3,4-DIMETHYL-5-PHENYL-[1,3,2]-OXAZASILOLIDINE is used as a key intermediate in the synthesis of pharmaceutical compounds, particularly those with chiral centers. Its enantioselective allylation properties enable the production of single-enantiomer drugs, which are essential for ensuring the desired therapeutic effects and minimizing potential side effects.
2. Synthesis of Tertiary Carbinamines:
(s,s)-2-ALLYL-2-CHLORO-3,4-DIMETHYL-5-PHENYL-[1,3,2]-OXAZASILOLIDINE is used as a reagent for the enantioselective allylation of ketimines, leading to the formation of tertiary carbinamines. These carbinamines are important building blocks in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and natural products.
Used in Chemical Research and Development:
In the field of chemical research and development, (s,s)-2-ALLYL-2-CHLORO-3,4-DIMETHYL-5-PHENYL-[1,3,2]-OXAZASILOLIDINE is used as a versatile reagent for the synthesis of complex organic molecules. Its ability to participate in enantioselective allylation reactions makes it a valuable asset in the development of new drugs and other specialty chemicals.
3. Enantioselective Allylation of Acylhydrazones:
(s,s)-2-ALLYL-2-CHLORO-3,4-DIMETHYL-5-PHENYL-[1,3,2]-OXAZASILOLIDINE is also used in the enantioselective allylation of acylhydrazones, which is an important reaction in the synthesis of biologically active compounds. This application further highlights the compound's utility in the pharmaceutical industry and other areas where chiral molecules are of interest.
Used in Fine Chemicals and Specialty Chemicals Industry:
(s,s)-2-ALLYL-2-CHLORO-3,4-DIMETHYL-5-PHENYL-[1,3,2]-OXAZASILOLIDINE is used as a reagent in the production of fine chemicals and specialty chemicals, where the need for enantioselective synthesis is crucial. Its application in this industry contributes to the development of high-quality products with specific chiral properties, which are essential for various applications, including pharmaceuticals, fragrances, and flavors.

Reaction

Versatile reagent for the enantioselective allylation of aldehydes and hydrazones.

Check Digit Verification of cas no

The CAS Registry Mumber 447440-43-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,7,4,4 and 0 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 447440-43:
(8*4)+(7*4)+(6*7)+(5*4)+(4*4)+(3*0)+(2*4)+(1*3)=149
149 % 10 = 9
So 447440-43-9 is a valid CAS Registry Number.

447440-43-9 Well-known Company Product Price

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  • Aldrich

  • (706671)  (4S,5S)-2-Allyl-2-chloro-3,4-dimethyl-5-phenyl-1-oxa-3-aza-2-silacyclopentane  

  • 447440-43-9

  • 706671-1G

  • 301.86CNY

  • Detail

447440-43-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (4S,5S)-2-chloro-3,4-dimethyl-5-phenyl-2-prop-2-enyl-1,3,2-oxazasilolidine

1.2 Other means of identification

Product number -
Other names (S,S)-Leighton reagent

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:447440-43-9 SDS

447440-43-9Relevant academic research and scientific papers

CHIRAL DIACHYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX

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Page/Page column 98-99, (2009/01/24)

The present invention provides diacylhydrazine ligands and chiral diacylhydrazine ligands for use with ecdysone receptor-based inducible gene expression systems. Thus, the present invention is useful for applications such as gene therapy, large scale prod

Toward a versatile allylation reagent: Practical, enantioselective allylation of acylhydrazones using strained silacycles

Berger, Richard,Rabbat, Philippe M. A.,Leighton, James L.

, p. 9596 - 9597 (2007/10/03)

A highly practical method for the enantioselective allylation of acylhydrazones has been developed. The previously reported strained silacycle reagent 1 reacts with a wide variety of acylhydrazones to give the hydrazide products with good enantioselectivi

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