447460-22-2

Basic information

• Product Name: 2,2,2-trifluoro-N-(1-{4-[2-(2-fluoro-benzenesulfonyl)-4-trifluoromethoxy-benzyl]-phenyl}-ethyl)-acetamide
• CAS NO: 447460-22-2
• Molecular Weight: 549.466
• Mol File: 447460-22-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2,2-trifluoro-N-(1-{4-[2-(2-fluoro-benzenesulfonyl)-4-trifluoromethoxy-benzyl]-phenyl}-ethyl)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trifluoro-N-(1-{4-[2-(2-fluoro-benzenesulfonyl)-4-trifluoromethoxy-benzyl]-phenyl}-ethyl)-acetamide(447460-22-2)
• EPA Substance Registry System: 2,2,2-trifluoro-N-(1-{4-[2-(2-fluoro-benzenesulfonyl)-4-trifluoromethoxy-benzyl]-phenyl}-ethyl)-acetamide(447460-22-2)

Safety Data

• Hazardous Substances Data: 447460-22-2(Hazardous Substances Data)

Upstream product

• 14135-38-7 bis(2-fluorophenyl) disulfide 
• 182141-70-4 N-[(1S)-1-(4-bromophenyl)ethyl]-2,2,2-trifluoroacetamide 
• 2354-91-8 (S)-2,2,2-trifluoro-(α-methylbenzyl)acetamide 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 659-28-9 p-trifluoromethoxybenzaldehyde 
• 447460-20-0 2,2,2-trifluoro-N-[1-(4-{[2-(2-fluoro-phenylsulfanyl)-4-trifluoromethoxy-phenyl]-hydroxy-methyl}-phenyl)-ethyl]-acetamide 
• 447460-19-7 2-(2-fluoro-phenylsulfanyl)-4-trifluoromethoxy-benzaldehyde 
• 447460-21-1 2,2,2-trifluoro-N-(1-{4-[2-(2-fluoro-phenylsulfanyl)-4-trifluoromethoxy-benzyl]-phenyl}-ethyl)-acetamide 

Downstream Products

• 447460-23-3 (S)-1-{4-[2-(2-Fluoro-benzenesulfonyl)-4-trifluoromethoxy-benzyl]-phenyl}-ethylamine 

Relevant articles and documents

Triaryl bis-sulfones as cannabinoid-2 receptor ligands: SAR studies

We recently reported that compound 1 is a potent inhibitor of the CB2 receptor with high selectivity over CB1. This paper describes the SAR development for this class of compounds. Variation of the substitution pattern on the aromatic rings, as well as th