4477-74-1Relevant academic research and scientific papers
Triterpenoid derivatives
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, (2008/06/13)
The present invention relates to the use of a compound of formula (I), or a pharmaceutically acceptable salt, crystal form, complex, hydrate, or hydrolysable ester thereof, in the preparation of a medicament for treating a patient suffering from leukaemia, cancer or other proliferative disorder. A further embodiment relates to the use a compound of formula (I) in an assay for detecting the phosphorylation state of cellular substrates. The present invention also relates to novel compounds of formula (I), and the chemical synthesis thereof.
HOMOGENEOUS HYDROGENATION AND DEUTERATION OF PENTACYCLIC TRITERPENOIDS: DOUBLE BONDS IN SIDE-CHAINS
Protiva, Jiri,Lepsa, Ludek,Klinotova, Eva,Klinot, Jiri,Krecek, Vaclav,Vystrcil, Alois
, p. 2734 - 2741 (2007/10/02)
The reduction of terminal double bonds in the side chains on the rings A and E of pentacyclic triterpenoids by means of tris(triphenylphosphine)rhodium chloride permits selective reduction of dienes and labelling with deuterium with a low scattering.The effect of the amount of the catalyst and the solvent used on the rate of reduction was studied in the case of 3β,28-diacetylbetulin.
