4480-50-6

Usage

Chemical prefix

Indicates the presence of a cyclopropyl group in a compound.

Cyclopropyl group

A three-membered carbon ring with one double bond, typically found in organic compounds.

Unique chemical and physical properties

Due to the strained nature of the cyclopropyl ring.

Variety of applications

Including pharmaceuticals, agrochemicals, and materials science.

Impact on reactivity

The presence of the 1-cyclopropylgroup can affect the compound's reactivity.

Impact on stability

The 1-cyclopropylgroup can influence the stability of the compound.

Impact on biological activity

The presence of the 1-cyclopropylgroup can affect the biological activity of the compound.

Importance in drug design

The 1-cyclopropylgroup is a crucial consideration in the design of pharmaceutical compounds.

Importance in chemical synthesis

The 1-cyclopropylgroup plays a significant role in the synthesis of various chemical compounds.

Upstream product

• 106-96-7 propargyl bromide 
• 1489-69-6 Cyclopropanecarboxaldehyde 
• 75-89-8 2,2,2-trifluoroethanol 
• 83961-09-5 3-cyclopropyl-1-cyclobutenyl nonaflate 

Relevant academic research and scientific papers

Silylcyclopropanes by Selective [1,4]-Wittig Rearrangement of 4-Silyl-5,6-dihydropyrans

4-Silyl-5,6-dihydropyrans undergo remarkably selective [1,4]-Wittig rearrangements to give silylcyclopropanes in good yields. The selectivity is independent of the silyl group, but it is influenced by the electronic character of the migrating center. Elec

Electrophilic cyclization and intermolecular acetalation of 2-(4- hydroxybut-1-yn-1-yl)benzaldehydes: Synthesis of diiodinated diepoxydibenzo[c,k][1,9]dioxacyclohexadecines

An expedient strategy for the preparation of diiodinated diepoxydibenzo[c,k][1,9]dioxacyclohexadecines from readily available 2-(4-hydroxybut-1-yn-1-yl)- benzaldehydes through electrophile-triggered tandem cyclization/ intermolecular acetalation sequence

Vinyl Cations, 38. Synthesis and Solvolysis of 3-Substituted 1-Cyclobutenyl Nonaflates

3-Methyl- (8a) and 3-cyclopropyl-1-cyclobutenyl nonaflate (8b) as well as 2-cyclopropyl-1-cyclobutenyl nonaflate (12) and the parent 1-cyclobutenyl nonaflate (3) were synthesized from the corresponding cyclobutanones and nonafluorobutanesulfonic anhydride (10).The solvolysis rates and the product compositions of the solvolyses in trifluoroethanol and trifluoroethanol/water mixtures were determined.All 1-cyclobutenyl nonaflates solvolyze via a SN1 mechanism involving the intermediate nonclassical 1-cyclobutenyl cation, which is additionally stabilized by the substituents in the 3-position.