449747-35-7Relevant academic research and scientific papers
Synthesis and antimicrobial activity of n-[(α-methyl)benzylidene]-(3-substituted-1,2,4-triazol-5-yl-thio) acetohydrazides
Ersan, Seyhan,Nacak, Sultan,Berkem, Rukiye
, p. 773 - 776 (1998)
In this study 18 new hydrazones have been synthesized by reacting ortho- or para-substituted acetophenones with (3-substituted-1,2,4-triazol-5-yl-thio)acetohydrazide in ethanol. The prepared compounds were tested for antimicrobial activity. The prepared compounds exhibited only poor activity against Gram (+) and Gram (-) bacteria with the minimal inhibitory concentration (MIC) ≥ 400 μg/ml. Moderate activity was observed against Candida species with MIC in the range 100-400 μg/ml.
