4498-71-9

Basic information

• Product Name: 1H-Indazole, 3-ethyl-
• Synonyms: 1H-Indazole, 3-ethyl-;3-Ethyl-1H-indazole
• CAS NO: 4498-71-9
• Molecular Formula: C9H10N2
• Molecular Weight: 146.1891
• Mol File: 4498-71-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1H-Indazole, 3-ethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indazole, 3-ethyl-(4498-71-9)
• EPA Substance Registry System: 1H-Indazole, 3-ethyl-(4498-71-9)

Safety Data

• Hazardous Substances Data: 4498-71-9(Hazardous Substances Data)

Usage

General Description

1H-Indazole, 3-ethyl-, also known as 3-ethylindazole, is a heterocyclic organic compound with the molecular formula C9H10N2. It is a colorless to light yellow liquid with a fruity odor, and it is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 3-ethylindazole has been found to exhibit biological activities such as anti-inflammatory, antibacterial, and antifungal properties, making it a valuable compound in the development of new drugs. This chemical is also used in the production of dyes, pigments, and rubber chemicals, and it is considered to be a hazardous substance that should be handled with care due to its potential health and environmental risks.

Upstream product

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Relevant articles and documents

Switchable Synthesis of 3-Substituted 1H-Indazoles and 3,3-Disubstituted 3H-Indazole-3-phosphonates Tuned by Phosphoryl Groups

3-Alkyl/aryl-1H-indazoles and 3-alkyl/aryl-3H-indazole-3-phosphonates were synthesized efficiently through a 1,3-dipolar cycloaddition reaction between α-substituted α-diazomethylphosphonates and arynes under simple reaction conditions. The product distribution was controlled by the phosphoryl group, which acted both as a tuning group and a traceless group in the reaction.

INDAZOLE- AND PYRROLOPYRIDINE-DERIVATIVE AND PHARMACEUTICAL USE THEREOF

The present invention relates to a novel indazole- or pyrrolopyridine-derivative, represented by the formula (1) below, that has an agonistic action or a partial agonistic action against serotonin-4 receptor, and a pharmaceutical composition comprising the same. Formula (1) [wherein each substituent is as defined in claim 1]

METHOD OF SYNTHESIZING 1H-INDAZOLE COMPOUNDS

A method is provided for synthesizing 1H-indazole compounds in which aromatic carbonyl compounds are reacted with a nitrogen source to form oximes which are then converted to 1H-indazoles.