44982-72-1

Basic information

• Product Name: 2-[(1-HYDROXY-2-METHYLPROPAN-2-YL)AMINO]-2-METHYLPROPAN-1-OL
• Synonyms: 2-[(1-HYDROXY-2-METHYLPROPAN-2-YL)AMINO]-2-METHYLPROPAN-1-OL;1-Propanol, 2,2'-iminobis[2-methyl-
• CAS NO: 44982-72-1
• Molecular Formula: C₈H₁₉NO₂
• Molecular Weight: 161.24196
• Mol File: 44982-72-1.mol

Chemical Properties

• Boiling Point: 136-142 °C(Press: 25 Torr)
• Appearance: /
• Density: 0.980±0.06 g/cm3(Predicted)
• PKA: 15.26±0.10(Predicted)
• CAS DataBase Reference: 2-[(1-HYDROXY-2-METHYLPROPAN-2-YL)AMINO]-2-METHYLPROPAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(1-HYDROXY-2-METHYLPROPAN-2-YL)AMINO]-2-METHYLPROPAN-1-OL(44982-72-1)
• EPA Substance Registry System: 2-[(1-HYDROXY-2-METHYLPROPAN-2-YL)AMINO]-2-METHYLPROPAN-1-OL(44982-72-1)

Safety Data

• Hazardous Substances Data: 44982-72-1(Hazardous Substances Data)

Upstream product

• 90032-83-0 3,3,5,5-tetramethyl-2-oxomorpholine 
• 91377-78-5 sodium 2-[2-methyl-1-hydroxy-2-propylamino]-2-methylpropionate 

Downstream Products

• 19412-12-5 3,3,5,5-tetramethylmorpholine 
• 93565-31-2 2,2,15,15-tetramethyl-1-aza-4,7,10,13-tetraoxacyclopentadecane 

Relevant articles and documents

Ligand-Enabled Catalytic C-H Arylation of Aliphatic Amines by a Four-Membered-Ring Cyclopalladation Pathway

A palladium-catalyzed C-H arylation of aliphatic amines with arylboronic esters is described, proceeding through a four-membered-ring cyclopalladation pathway. Crucial to the successful outcome of this reaction is the action of an amino-acid-derived ligand. A range of hindered secondary amines and arylboronic esters are compatible with this process and the products of the arylation can be advanced to complex polycyclic molecules by sequential C-H activation reactions. Four corners: A palladium-catalyzed C-H arylation of aliphatic amines with arylboronic esters is described to proceed by a four-membered-ring cyclopalladation pathway. Crucial to the successful outcome of this reaction is the action of an amino-acid-derived ligand. A range of hindered secondary amines and arylboronic esters are compatible with this process and the products of the arylation can be advanced to complex polycyclic molecules by sequential C-H activation reactions.

Polysubstituted 2-morpholones, related compounds, processes for their preparation, and U-V light stabilized compositions

An essentially single stage reaction has been discovered in which a disubstituted ethanolamine, that is, a 2,2'-substituted-2-aminoethanol, may be reacted with a haloform and a carbonyl containing compound selected from the group consisting of monoketones and benzaldehyde, in the presence of an alkali metal hydroxide, and optionally in the presence of a phase transfer catalyst, to produce an alkali metal hydroxyethylaminoacetate ("HEAA") which has N-adjacent C atoms on which there are a total of at least three substituents (hence "polysubstituted"), and one or both pairs of substituents on each N-adjacent C atom may be cyclized. The HEAA may be cyclized by the action of a mineral acid to produce a 2-morpholone hydrochloride which is characterized by having a total of at least three substituents on the N-adjacent C atoms of the ring. The 2-morpholone so produced may be reduced to a polysubstituted aminodiol. The aminodiol so produced may be cyclized with an alkane sulfonic acid to yield a polysubstituted morpholine which could not otherwise have been made. The aminodiol may also be alkylated to produce diethers with polysubstituted N-adjacent C atoms. If the aminodiol is tosylated, a polysubstituted crown ether is produced with plural polyalkylene groups. The foregoing HEAA and related compounds are used as u-v light stabilizers in novel compositions in which a small but effective amount of one or more of the HEAA and related compounds is incorporated, in an amount sufficient to produce desirable stabilization against degradation by u-v light in a wide variety of organic materials.