90032-83-0Relevant articles and documents
Continuous-Flow Synthesis and Derivatization of Aziridines through Palladium-Catalyzed C(sp3)?H Activation
Zakrzewski, Jacek,Smalley, Adam P.,Kabeshov, Mikhail A.,Gaunt, Matthew J.,Lapkin, Alexei A.
, p. 8878 - 8883 (2016)
A continuous-flow synthesis of aziridines by palladium-catalyzed C(sp3)?H activation is described. The new flow reaction could be combined with an aziridine-ring-opening reaction to give highly functionalized aliphatic amines through a consecutive process. A predictive mechanistic model was developed and used to design the C?H activation flow process and illustrates an approach towards first-principles design based on novel catalytic reactions.
Efficient selective oxidation of alcohols to aldehydes catalyzed by a morpholinone nitroxide
Dong, Zhenhua,Gao, Pengwei,Xiao, Yongmei
, p. 3380 - 3388 (2019/11/05)
Efficient chemoselective oxidation of primary alcohols to the corresponding aldehydes is described. The transformation is promoted by a catalytic morpholinone nitroxide radical catalyst which can be easily synthesized. A broad range of substrates includin
Highly active metal-free catalysts for hydrogenation of unsaturated nitrogen-containing compounds
Sumerin, Victor,Chernichenko, Konstantin,Nieger, Martin,Leskelae, Markku,Rieger, Bernhard,Repo, Timo
scheme or table, p. 2093 - 2110 (2011/11/06)
New highly active ansa-ammonium borate catalysts for the direct metal-free hydrogenation of imines were prepared by tuning of the basicity and steric bulkiness of their amine moieties. The highest catalytic activity among previously reported organocatalytic systems was shown for a wide range of nitrogen-containing substrates. The first example of asymmetric imine hydrogenation based on the ansa-ammonium borate concept was demonstrated. Furthermore, effective catalyst recovery by extraction of the acidic solution with an organic solvent followed by dehydration with TMSBr was elaborated. The initial findings highlight the development of more effective chiral ansa-ammonium borates for enantioselective hydrogenation. Therefore, the progress achieved in the ansa-ammonium borate concept makes it very promising for further elaboration with the aim to obtain industrially applicable catalysts. Copyright