4499-84-7

Basic information

• Product Name: 1,4-bis(4-methylphenyl)benzene
• Synonyms: 4,4''-dimethyl-1,1':4',1''-terphenyl
• CAS NO: 4499-84-7
• Molecular Formula: C₂₀H₁₈
• Molecular Weight: 258.3569
• Mol File: 4499-84-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1,4-bis(4-methylphenyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-bis(4-methylphenyl)benzene(4499-84-7)
• EPA Substance Registry System: 1,4-bis(4-methylphenyl)benzene(4499-84-7)

Safety Data

• Hazardous Substances Data: 4499-84-7(Hazardous Substances Data)

Usage

Structure

It consists of a benzene ring with two methylphenyl groups attached at the 1 and 4 positions.

Physical State

It is a colorless, odorless solid.

Solubility

Insoluble in water but soluble in organic solvents.

Uses

Commonly used in the production of polymers and plastics, synthesis of various organic compounds, as a heat transfer fluid, and as a component in electronic materials and liquid crystals.

Industrial Applications

It has a variety of industrial applications.

Safety Precautions

It may be harmful if ingested or inhaled and can cause skin and eye irritation, so it should be handled with care.

Upstream product

• 95814-02-1 1,4-di(3-methylphenyl)-1,3-cyclohexadiene 
• 624-38-4 para-diiodobenzene 
• 17933-03-8 m-tolylboronic acid 
• 106-37-6 1.4-dibromobenzene 
• 67628-58-4 bis(4-methoxyphenyl) sulfate 
• 28987-79-3 m-tolylmagnesium bromide 
• 63262-06-6 1,4-dibromo-2,5-diiodobenzene 
• 599-89-3 4-chlorophenyl p-toluenesulfonate 
• 637-88-7 1,4-Cyclohexanedione 

Relevant articles and documents

Synthesis of symmetrical terphenyl derivatives by PdCl 2-catalyzed Suzuki-Miyaura reaction of dibromobenzene using 3-(diphenylphosphino)propanoic acid as a ligand

A simple and efficient catalytic system for PdCl2 catalyzing the Suzuki-Miyaura reaction of dibromobenzene and arylboronic acid has been developed by using 3-(diphenylphosphino)propanoic acid as a ligand in dimethylsulfoxide at 100 °C. Using this method, a series of symmetrical terphenyl derivatives were obtained with remarkably good yields, up to 93%.

3,3″-dimethyl-1,1′:4′,1″-terphenyl

The title compound, C20H18, is centrosymmetric and adopts a twisted conformation. This result contrasts related unsubstituted systems, where rotational disorder is inevitably found. The different behaviour is rationalized in terms of the absence of π-π interactions in the lattice of the title compound.

N-heterocyclic carbene-palladium(II)-1-methylimidazole complex-catalyzed Suzuki-Miyaura coupling of aryl sulfonates with arylboronic acids

A well-defined NHC-Pd(II)-Im complex 1 was found to be an effective catalyst for the Suzuki-Miyaura coupling of aryl sulfonates including tosylates and phenylsulfonates with arylboronic acids, giving the desired coupling products in good to high yields. Acceptable yields can also be achieved even by using the less reactive mesylates as the substrates. It is worthy of noting here that this is the first example of NHC-Pd(II) complex-catalyzed Suzuki-Miyaura coupling of aryl sulfonates with arylboronic acids, enriching an inexpensive, convenient, and alternative method for the synthesis of biaryl compounds.