450408-27-2Relevant academic research and scientific papers
Daphniphyllum Alkaloids. 15. Total Syntheses of (+/-)-Methyl Homodaphniphyllate and (+/-)-Daphnilactone A
Heathcock, Clayton H.,Ruggeri, Roger B.,McClure, Kim F.
, p. 2585 - 2594 (1992)
Biomimetic total syntheses of (+/-)-daphnilactone A (6) and (+/-)-methyl homodaphniphyllate (4) have been carried out.The syntheses began with the preparation of tricyclic lactone ether 18d, which was reduced to diol 19d with LiAlH4.Oxidation of 19d gave
Tetrabutylammonium tribromide (TBATB) as an efficient generator of HBr for an efficient chemoselective reagent for acetalization of carbonyl compounds
Gopinath, Rangam,Haque, Sk. Jiaul,Patel, Bhisma K.
, p. 5842 - 5845 (2007/10/03)
Acyclic and cyclic acetals of various carbonyl compounds were obtained in excellent yields under a mild reaction condition in the presence of trialkyl orthoformate and a catalytic amount of tetrabutylammonium tribromide (TBATB) in absolute alcohol. Chemoselective acetalization of an aldehyde in the presence of ketone, unsymmetrical acetal formation, shorter reaction times, mild reaction conditions, the stability of acid-sensitive protecting groups, high efficiencies, facile isolation of the desired products, and the catalytic nature of the reagent make the present methodology a practical alternative.
