450412-21-2 Usage
Molecular structure
Substituted aromatic compound with a benzene ring and attached bromine, cyanide, and iodine groups
Functional groups
Bromine, cyanide, and iodine
Applications
a. Building block in organic synthesis
b. Versatile intermediate for preparation of functionalized benzene derivatives
c. Used in production of pharmaceuticals, agrochemicals, and dyes
Importance in research
a. Valuable reagent for organic chemistry research
b. Unique structural properties and reactivity
Position of substituents
a. Bromine at the 1st position
b. Cyanide at the 2nd position
c. Iodine at the 3rd position
Physical state
Likely a solid at room temperature (based on molecular weight and structure)
Solubility
Soluble in organic solvents such as dichloromethane, acetone, and ethanol (based on the presence of aromatic ring and functional groups)
Stability
Stable under normal conditions, but may be sensitive to heat, light, or strong oxidizing agents (due to the presence of halogen atoms)
Hazards
Potentially toxic and harmful if inhaled, ingested, or absorbed through the skin (due to the presence of cyanide group)
Check Digit Verification of cas no
The CAS Registry Mumber 450412-21-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,0,4,1 and 2 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 450412-21:
(8*4)+(7*5)+(6*0)+(5*4)+(4*1)+(3*2)+(2*2)+(1*1)=102
102 % 10 = 2
So 450412-21-2 is a valid CAS Registry Number.
450412-21-2Relevant articles and documents
Ring opening of aziridines with ortho-bromophenyl metal reagents: synthesis of 2-substituted indolines
Michaelis, David J.,Dineen, Thomas A.
body text, p. 1920 - 1923 (2009/08/17)
Stabilized ortho-bromo phenyllithium reagents, generated via lithium-halogen exchange of aryl iodides, undergo regioselective ring opening of mono-substituted N-Boc, N-Cbz, and N-tosyl-protected aziridines in good to excellent yields. The resulting ortho-
Direct ortho cupration: A new route to regioselectively functionalized aromatics
Usui, Shinya,Hashimoto, Yuichi,Morey, James V.,Wheatley, Andrew E. H.,Uchiyama, Masanobu
, p. 15102 - 15103 (2008/09/17)
We have developed a direct regio- and chemoselective method for generating functionalized aromatic cuprate compounds through deprotonative directed ortho cupration using TMP(tetramethylpiperidino)-cuprates (R(TMP)Cu(CN)Li2; R = alkyl, phenyl, o
