450841-11-9

Upstream product

• 33821-61-3 3-((dimethylamino)methylene)-6-methyl-2H-pyran-2,4(3H)-dione 
• 108-42-9 3-chloro-aniline 

Downstream Products

• 450841-14-2 1-(3-chlorophenyl)-6-methyl-4-oxo-1,4-dihydro-3-pyridinecarboxamide 
• 797783-26-7 1-(3-chloro-phenyl)-6-({[3-(4-cyano-benzyl)-3H-imidazol-4-ylmethyl]-amino}-methyl)-4-oxo-1,4-dihydro-pyridine-3-carbonitrile 
• 797783-37-0 6-azidomethyl-1-(3-chloro-phenyl)-4-oxo-1,4-dihydro-pyridine-3-carbonitrile 
• 797783-32-5 6-aminomethyl-1-(3-chloro-phenyl)-4-oxo-1,4-dihydro-pyridine-3-carbonitrile 
• 797783-36-9 1-(3-chloro-phenyl)-6-hydroxymethyl-4-oxo-1,4-dihydro-pyridine-3-carbonitrile 
• 450841-22-2 6-(bromomethyl)-1-(3-chlorophenyl)-4-oxo-1,4-dihydro-3-pyridinecarbonitrile 
• 797783-35-8 1-(3-chloro-phenyl)-6-formyl-4-oxo-1,4-dihydro-pyridine-3-carbonitrile 

Relevant academic research and scientific papers

Farnesyltransferase inhibitors

Substituted imidazoles and thiazoles having the formula are useful for inhibiting farnesyltransferase. Also disclosed are farnesyltransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient.

Farnesyltransferase inhibitors

Substituted imidazoles and thiazoles having the formula are useful for inhibiting farnesyltransferase. Also disclosed are farnesyltransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient.