451-25-2

Basic information

• Product Name: 2-Pentanone,4-(4-methylphenyl)-
• Synonyms: 2-Pentanone,4-p-tolyl- (6CI,8CI); Curcumone
• CAS NO: 451-25-2
• Molecular Formula: C12H16 O
• Molecular Weight: 176.258
• Mol File: 451-25-2.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 2-Pentanone,4-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentanone,4-(4-methylphenyl)-(451-25-2)
• EPA Substance Registry System: 2-Pentanone,4-(4-methylphenyl)-(451-25-2)

Safety Data

• Hazardous Substances Data: 451-25-2(Hazardous Substances Data)

Upstream product

• 33604-67-0 (4-methylphenyl)azo 4-methylphenyl sulfone 
• 3102-33-8 trans-3-penten-2-one 
• 5395-43-7 tri(p-tolyl)antimony 
• 87856-04-0 chlorobis(4-methylphenyl)antimony 
• 118527-87-0 methyl 3-p-tolyl-5-hexanoate 
• 121944-95-4 4-(2-Methyl-[1,3]dioxolan-2-yl)-3-p-tolyl-butyraldehyde 
• 122-00-9 para-methylacetophenone 
• 624-31-7 4-tolyl iodide 
• 107-87-9 2-Pentanone 
• 536-50-5 CH₃C₆H₄CH(CH₃)OH 
• 108-22-5 Isopropenyl acetate 
• 128816-30-8 1-(4-methylphenyl)ethyl trimethylsilyl ether 
• 116428-36-5 methyl (3SR,5RS)-6-hydroxy-3-p-tolyl-5-(trimethylsilyl)hexenoate 
• 121944-94-3 methyl 5-oxo-3-(p-tolyl)hexenoate 

Downstream Products

• 61235-22-1 4-p-Tolyl-2-trimethylsilyloxy-penten-⁽¹⁾ 
• 100-21-0 terephthalic acid 
• 61235-23-2 6-p-Tolyl-2-hydroxy-2-methyl-heptanon-⁽⁴⁾ 
• 38142-58-4 (+/-)-ar-turmerone 
• 17701-23-4 4-p-tolyl-pentan-2-one semicarbazone 
• 586-89-0 4-acetyl-benzoic acid 
• 122-00-9 para-methylacetophenone 

Relevant articles and documents

Palladium-catalyzed site-selective arylation of aliphatic ketones enabled by a transient ligand

Transition metal-catalyzed direct C-H bond functionalization enabled by transient ligands has become an attractive topic. Here we report a palladium-catalyzed site-selective arylation of β-C(sp3)-H bonds in aliphatic ketones with β-alanine as the transient ligand.

Rhenium complex-catalyzed coupling reaction of enol acetates with alcohols

The reaction of enol acetates with alcohols in the presence of a catalytic amount of a rhenium complex, such as ReBr(CO)5, produced the corresponding ketones and aldehydes in moderate to good yields. It was suggested that the preparation of an ether, an intermolecular dehydrated product, was the first step of the reaction.

α-Alkylation of carbonyl compounds by direct addition of alcohols to Enol acetates

A practical α-alkylation of ketones and aldehydes has been achieved by the direct addition of alcohols to enol acetates. The moderate Lewis acidity of InI3, CaBr3, and FeBr3 is a key factor in the catalytic cycle, and many different alcohols and enol acetates have been successfully used in this procedure.