4511-34-6Relevant academic research and scientific papers
Direct synthesis of magnesium porphine via 1-formyldipyrromethane
Dogutan, Dilek Kiper,Ptaszek, Marcin,Lindsey, Jonathan S.
, p. 5008 - 5011 (2008/02/07)
(Chemical Equation Presented) The reaction of 1-formyldipyrromethane (100 mM) in toluene at 115°C containing DBU (10 mol equiv) and MgBr2 (3 mol equiv) in the presence of air affords the magnesium chelate Mg(II) porphine in 30-40% yield. The advantages of the new method include simplicity, high concentration, chromatography-free purification, gram-scale synthesis, and avoidance of the poorly soluble free base porphine. Mg(II) porphine exhibits good solubility in common organic solvents and is a valuable core scaffold for derivatization.
Methods and intermediates for the synthesis of porphyrins
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Page/Page column 12-13; 14-15; 27, (2008/06/13)
A method of making a porphyrin (I) is carried out by condensing (i) a bis(imino)dipyrromethane of Formula II: with (ii) a dipyrromethaneto produce a reaction product; then (b) optionally oxidizing said reaction product with an oxidizing agent; and then (c) optionally demetallating said reaction product to produce the porphyrin. Methods of making compounds of Formula II are also described.
Synthesis and photochemical reactivity of bilirubin model compounds
Groot, J. A. de,Steen, R. van der,Fokkens, R.,Lugtenburg, J.
, p. 35 - 40 (2007/10/02)
The bilirubin model compounds 1, 2 and 3 were prepared in good yield.The photochemistry of 1, 2 and 3, which all have the 4Z,15Z form, was investigated; they show a Z-E isomerisation to the 4Z,15E and the 4E,15E isomers.Unlike the isomers of 1, those of the compounds 2 and 3, could be isolated in a pure form.
