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2-(((benzyloxy)carbonyl)amino)-2-methylbutanoic acid is a complex organic compound with the molecular formula C14H19NO4. It is a derivative of amino acids, featuring a benzyloxycarbonyl (Cbz) protecting group, which is commonly used in peptide synthesis to protect the amino group. 2-(((benzyloxy)carbonyl)amino)-2-methylbutanoic acid consists of a 2-methylbutanoic acid backbone with an amino group attached to the second carbon, which is further protected by the benzyloxycarbonyl group. The presence of this protecting group makes it a valuable intermediate in the synthesis of peptides and other biologically active molecules, as it allows for the controlled formation of peptide bonds while preventing unwanted side reactions. The compound is also known for its potential applications in pharmaceutical research and development, particularly in the creation of new drugs and therapeutic agents.

4512-49-6

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4512-49-6 Usage

Molecular structure

2-(((benzyloxy)carbonyl)amino)-2-methylbutanoic acid consists of a 2-methylbutanoic acid backbone, an amino group, and a benzyloxy carbonyl group.

Benzyloxy carbonyl group

Also known as a benzyl ester, it contains a benzene ring attached to a carbonyl group (C=O).

Amino group

Contains a nitrogen atom (N) bonded to the carbon atom of the carbonyl group.

Potential applications

The compound may have potential applications in the field of organic synthesis and pharmaceuticals.

Unique structure

The combination of the 2-methylbutanoic acid backbone, amino group, and benzyloxy carbonyl group gives the compound a unique structure.

Functional groups

The presence of the amino group and benzyloxy carbonyl group provides the compound with various functional properties, which can be utilized in chemical reactions and pharmaceutical development.

Check Digit Verification of cas no

The CAS Registry Mumber 4512-49-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,1 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4512-49:
(6*4)+(5*5)+(4*1)+(3*2)+(2*4)+(1*9)=76
76 % 10 = 6
So 4512-49-6 is a valid CAS Registry Number.

4512-49-6Relevant academic research and scientific papers

PYRAZOLE DERIVATIVES AS SGC STIMULATORS

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Paragraph 00329, (2016/04/09)

There are described imidazole and pyrazole derivatives which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.

Identification and design of a novel series of MGAT2 inhibitors

Barlind, Jonas G.,Buckett, Linda K.,Crosby, Sharon G.,Davidsson, ?jvind,Emten?s, Hans,Ertan, Anne,Jurva, Ulrik,Lemurell, Malin,Gutierrez, Pablo Morentin,Nilsson, Karolina,O'Mahony, Gavin,Petersson, Annika U.,Redzic, Alma,W?gberg, Fredrik,Yuan, Zhong-Qing

, p. 2721 - 2726 (2013/06/27)

[Acyl CoA]monoacylglycerol acyltransferase 2 (MGAT2) is of interest as a target for therapeutic treatment of diabetes, obesity and other diseases which together constitute the metabolic syndrome. In this Letter we report our discovery and optimisation of a novel series of MGAT2 inhibitors. The development of the SAR of the series and a detailed discussion around some key parameters monitored and addressed during the lead generation phase will be given. The in vivo results from an oral lipid tolerance test (OLTT) using the MGAT2 inhibitor (S)-10, shows a significant reduction (68% inhibition relative to nave, p 0.01) in plasma triacylglycerol (TAG) concentration.

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