451491-93-3

Upstream product

• 4083-64-1 Tosyl isocyanate 
• 88039-49-0 (Z)-ethyl 2-(bromomethyl)-3-phenylacrylate 
• 70-55-3 toluene-4-sulfonamide 
• 37442-45-8 ethyl 2-(hydroxy(phenyl)methyl)propenoate 
• 105479-98-9 ethyl 2-(acetoxy(phenyl)methyl)acrylate 
• 451491-99-9 C₂₀H₂₁NO₆S 

Downstream Products

• 352521-56-3 ethyl 1-tosyl-1,2-dihydroquinoline-3-carboxylate 
• 1017264-75-3 C₂₃H₂₆BrNO₄S 
• 246868-72-4 2-benzoyl-3-phenylpyrrole-4-carboxylic acid ethyl ester 
• 50741-46-3 ethyl 3-quinolinecarboxylate 

Relevant academic research and scientific papers

Palladium-catalyzed domino cyclization (5-exo/3-exo), ring- expansion by palladium rearrangement, and aromatization: An expedient synthesis of 4-arylnicotinates from Morita-Baylis-Hillman adducts

Various 4-arylnicotinate derivatives were synthesized via a palladium-catalyzed cascade reaction of N-(2-bromoallyl)-N-cinnamyltosylamides in a one-pot procedure in good yields. The reaction involves a domino 5-exo/3-exo carbopalladation, ring-expansion b

Synthesis of unsaturated β-amino acid derivatives from carbamates of the Baylis-Hillman products

By treatment with a catalytic amount of DBU in DCM, N-p-toluenesulphonyl carbamates 6a-c, prepared starting from the corresponding Baylis-Hillman adducts, gave (E)-2-(p-toluenesulphonylaminomethyl)propenoates 3a-c, exclusively. On the contrary, changing D

Synthesis of quinolines from the Baylis-Hillman acetates via the oxidative cyclization of sulfonamidyl radical as the key step

Ethyl 3-quinolinecarboxylates 5 were synthesized in good to moderate yields from the Baylis-Hillman acetates 1 via the oxidative cyclization reaction of the N-tosylamidyl radical, which was generated from the rearranged tosylamide derivatives 2 by iodoben