246868-72-4Relevant academic research and scientific papers
Synthesis of poly-substituted pyrroles starting from the Baylis-Hillman adducts
Lee, Hyun Seung,Kim, Jeong Mi,Kim, Jae Nyoung
, p. 4119 - 4122 (2008/02/03)
We synthesized poly-substituted pyrrole derivatives 4a-e, 7a-c and 10a-d from the reaction of phenacyl bromide and the aza-Baylis-Hillman adducts 1a-d or their rearranged derivatives 5a-e. The pyrroles were synthesized via the successive N-alkylation, Mic
The application of vinylogous iminium salt derivatives to an efficient synthesis of the pyrrole containing alkaloids Rigidin and Rigidin E
Gupton, John T.,Banner, Edith J.,Scharf, Austin B.,Norwood, Bradley K.,Kanters, Rene P.F.,Dominey, Raymond N.,Hempel, Jonathan E.,Kharlamova, Anastasia,Bluhn-Chertudi, Itta,Hickenboth, Charles R.,Little, Barrett A.,Sartin, Melissa D.,Coppock, Matthew B.,Krumpe, Keith E.,Burnham, Bruce S.,Holt, Herman,Du, Karen X.,Keertikar, Kartik M.,Diebes, Anthony,Ghassemi, Shahnaz,Sikorski, James A.
, p. 8243 - 8255 (2007/10/03)
Studies directed on the synthesis of the pyrrole containing marine natural products Rigidin and Rigidin E via vinylogous iminium salts are described. The successful strategy relies on the formation of a 2,4-disubstituted pyrrole from a vinamidinium salt f
