452056-94-9

Upstream product

• 452056-89-2 N-{4-[5-(4-fluorophenyl)-3-propyl-2-thioxo-2,3-dihydro-1H-imidazol-4-yl]pyridin-2-yl}acetamide 
• 74-88-4 methyl iodide 
• 452056-84-7 N-{4-[5-(4-fluorophenyl)-1-oxy-3-propyl-3H-imidazol-4-yl]pyridin-2-yl}acetamide 
• 452056-82-5 N-{4-[2-(4-fluorophenyl)-2-hydroxyliminoacetyl]pyridin-2-yl}acetamide 

Relevant academic research and scientific papers

Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes

A series of polysubstituted pyridin-4-yl imidazole inhibitors of p38 MAP (mitogen-activated protein) kinase was prepared as small molecular anticytokine agents and drug candidates for the treatment of chronic inflammatory diseases. The contribution of sub