453-09-8

Basic information

• Product Name: Brn 1732049
• Synonyms: 1,3-Propanediol, 2-fluoro-;2-Deoxy-2-fluoroglycerol;2-Fluoro-1,3-propanediol;Brn 1732049;2-fluoropropane-1,3-diol
• CAS NO: 453-09-8
• Molecular Formula: C₃H₇FO₂
• Molecular Weight: 94.0848832
• Mol File: 453-09-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 223.3°Cat760mmHg
• Flash Point: 88.9°C
• Appearance: /
• Density: 1.192g/cm³
• CAS DataBase Reference: Brn 1732049(CAS DataBase Reference)
• NIST Chemistry Reference: Brn 1732049(453-09-8)
• EPA Substance Registry System: Brn 1732049(453-09-8)

Safety Data

• Hazardous Substances Data: 453-09-8(Hazardous Substances Data)

Upstream product

• 685-88-1 fluoromalonic acid diethyl ester 
• 344-14-9 dimethyl 2-fluoromalonate 
• 32804-09-4 3-acetoxy-2-fluoro-propan-1-ol 
• 33573-99-8 2-fluoro-1,3-bis-trityloxy-propane 
• 1993-92-6 2-fluoro-3-hydroxypropionic acid ethyl ester 

Downstream Products

• 900809-19-0 3-{[tert-butyl(diphenyl)silyl]oxy}-2-fluoropropan-1-ol 
• 433-07-8 2-fluoropropane-1,3-diyl bis(4-methylbenzenesulfonate) 

Relevant articles and documents

Synthesis and evaluation of N-(4-benzylphenyl)piperazines as VGF inducers

A series of compounds was discovered that induce the production of VGF mRNA in SH-SY5Y cells and exhibit cytoprotection under tunicamycin induced endoplasmic reticulum (ER) stress. The aminophenol ring and linker chain of the template SUN N8075 (1) was modified to yield compounds with higher efficacy and lower propensity for adverse effects.

6,7-DIHYDRO-5H-PYRAZOLO[5,1-B][1,3]OXAZINE-2-CARBOXAMIDE COMPOUNDS

The present invention is directed to PDE4B inhibitors of Formula I: (I) or a pharmaceutically acceptable salt thereof, wherein the substituents R1, R2, R 3, and R 4are as defined herein. The invention is also di

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