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Brn 1732049, also known as 1-(4-Bromophenyl)-2-phenyl-1-ethanone, is an organic compound with the molecular formula C15H12BrO. It is a derivative of acetophenone, characterized by the presence of a bromine atom attached to the phenyl ring. This chemical is primarily used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its reactivity and structural properties, Brn 1732049 can be further functionalized to produce a range of valuable compounds.

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  • 453-09-8 Structure
  • Basic information

    1. Product Name: Brn 1732049
    2. Synonyms: 1,3-Propanediol, 2-fluoro-;2-Deoxy-2-fluoroglycerol;2-Fluoro-1,3-propanediol;Brn 1732049;2-fluoropropane-1,3-diol
    3. CAS NO:453-09-8
    4. Molecular Formula: C3H7FO2
    5. Molecular Weight: 94.0848832
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 453-09-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 223.3°Cat760mmHg
    3. Flash Point: 88.9°C
    4. Appearance: /
    5. Density: 1.192g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Brn 1732049(CAS DataBase Reference)
    10. NIST Chemistry Reference: Brn 1732049(453-09-8)
    11. EPA Substance Registry System: Brn 1732049(453-09-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 453-09-8(Hazardous Substances Data)

453-09-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 453-09-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,5 and 3 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 453-09:
(5*4)+(4*5)+(3*3)+(2*0)+(1*9)=58
58 % 10 = 8
So 453-09-8 is a valid CAS Registry Number.

453-09-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-fluoropropane-1,3-diol

1.2 Other means of identification

Product number -
Other names 2-Fluor-propan-1,3-diol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:453-09-8 SDS

453-09-8Relevant articles and documents

Synthesis and evaluation of N-(4-benzylphenyl)piperazines as VGF inducers

Toba, Tetsuya,Suzuki, Ryosuke,Futamura-Takahashi, Junko,Kawamoto, Yoshito,Tamura, Shigeki,Kuroda, Mariko,Shimmyo, Yoshiari,Kadokura, Michinori,Goto, Kazumichi,Inoue, Teruyoshi,Muto, Tsuyoshi,Annoura, Hirokazu

, p. 2528 - 2532 (2018/06/06)

A series of compounds was discovered that induce the production of VGF mRNA in SH-SY5Y cells and exhibit cytoprotection under tunicamycin induced endoplasmic reticulum (ER) stress. The aminophenol ring and linker chain of the template SUN N8075 (1) was modified to yield compounds with higher efficacy and lower propensity for adverse effects.

NMDA RECEPTOR MODULATORS AND USES THEREOF

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Paragraph 00183, (2018/07/29)

Disclosed herein, in part, are heteroaromatic compounds and methods of use in treating neuropsychiatric disorders, e.g., schizophrenia and major depressive disorder. Pharmaceutical compositions and methods of making heteroaromatic compounds are provided. The compounds are contemplated to modulate the NMDA receptor.

6,7-DIHYDRO-5H-PYRAZOLO[5,1-B][1,3]OXAZINE-2-CARBOXAMIDE COMPOUNDS

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Page/Page column 57, (2017/09/09)

The present invention is directed to PDE4B inhibitors of Formula I: (I) or a pharmaceutically acceptable salt thereof, wherein the substituents R1, R2, R 3, and R 4are as defined herein. The invention is also di

METHOD FOR PRODUCING -FLUOROALCOHOL

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Paragraph 0059, (2013/11/05)

A production method of a β-fluoroalcohol includes performing a reaction of an α-fluoroester with hydrogen gas (H2) in the presence of a specific ruthenium complex (i.e. a ruthenium complex of the general formula [2], preferably a ruthenium complex of the general formula [4]). This production method can employ a suitable hydrogen pressure of 1 MPa or less by the use of such a specific ruthenium complex and does not require a high-pressure gas production facility when put in industrial practice. In addition, this production method can remarkably reduce the amount of catalyst used therein (to e.g. a substrate/catalyst ratio of 20,000) in comparison to the substrate/catalyst ratio conventional reduction of α-fluoroalcohol. It is possible by these reduction in hydrogen pressure and catalyst amount to largely reduce the production cost of the β-fluoroalcohol.

INHIBITORS OF AKT ACTIVITY

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Page/Page column 61, (2008/06/13)

Invented are novel 1 H-imidazo[4,5-c]pyridin-2-yl compounds, the use of such compounds as inhibitors of protein kinase B activity and in the treatment of cancer and arthritis.

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